持续小剂量西地那非治疗早泄合并下尿路症状  

Daily low-dose sildenafil therapy on premature ejaculation concurrent with lower urinary tract symptoms

作　　者：陈洪德[1] 张奕荣[1] 翁志梁[1] 李澄棣[1] 

机构地区：[1]温州医学院附属第一医院泌尿外科,温州325000

出　　处：《中国男科学杂志》2010年第6期56-58,共3页Chinese Journal of Andrology

摘　　要：目的研究持续小剂量西地那非治疗早泄(PE)对良性前列腺增生症(BPH)引起的下尿路症状(LUTS)的影响。方法 82例PE同时伴有BPH的研究对象,随机分为2组,分别服用为期3个月的小剂量西地那非(A组)和左洛复(B组)。在治疗前后行中国早泄指数评估表(CIPE)、国际前列腺症状评分表(IPSS)评分,比较其治疗前、后CIPE和IPSS评分。结果治疗后A组CIPE明显增高,IPSS评分明显下降(P<0.01);B组CIPE明显增高(P<0.01),但IPSS评分轻度下降(P>0.05)。结论治疗中老年性PE合并BPH,小剂量西地那非既能有效治疗PE,又能改善由BPH引起的LUFS症状。Objective To assess the effect of low dose Sildenafil for the lower urinary tract symptoms （LUTS） of BPH patients with PE. Methods A total of 82 PE patients with BPH were randomly divided into 2 groups. Patients received 12-week therapy of Sildenafil （group A） and Fluoxetine （group B）, respectively. The score of CIPE and IPSS were recorded and analyzed pre- and post intervention. Results In group A, the score of CIPE increased significantly （P〈0.01）, and the IPSS score decreased significantly （P〈0.01） after treatment. In group B, the score of CIPE increased significantly （P〈0.01）, but the IPSS score slightly decreased（P〉0.05）. Conclusion Low dose sildenafil was effective not only for PE treatment, but also for improving LUTS of BPH. It provided a new idea for treatment of BPH patients with PE.

关 键 词：早泄 前列腺增生 下尿路症状 西地那非 

分 类 号：R698[医药卫生—泌尿科学] R697.32[医药卫生—外科学]