舟山海岛地区甲状腺结节影响因素病例对照研究  

Related factors of thyroid nodule in residents of Zhoushan Archipelago

作　　者：竺王玉[1] 刘晓光[1] 周世权[1] 王晔恺[1] 胡晓斐[1] 郑笑娟[1] 赵臣银[1] 袁惠萍[1] 张永奎[1] 

机构地区：[1]浙江省舟山市人民医院,舟山316000

出　　处：《中国公共卫生》2010年第7期942-943,共2页Chinese Journal of Public Health

基　　金：国家星火计划项目(2008GA700174);浙江省科技厅面上项目(2008C33043)

摘　　要：目的分析浙江省舟山市海岛地区居民甲状腺结节患病的危险因素。方法按整群随机抽样法,对舟山市海岛居民进行流行病学问卷调查、甲状腺B超检查及尿碘检测;将甲状腺结节阳性者与B超下甲状腺无病变者按性别、年龄、城乡、职业以1:1配对各831人,进行病例对照研究;采用单因素及多因素Logistic回归模型分析相关的危险因素。结果年收入为甲状腺结节的保护因素(P=0.014,OR=0.875,95%CI=0.589～0.998),年收入在3～5万元者与其他收入者比较不易患甲状腺结节(P=0.042);吸烟者甲状腺结节患病率较高,尿碘值在100～199μg/L者甲状腺结节患病率较低(P<0.05)。结论海岛居民饮食生活习惯、碘营养水平等与甲状腺结节发生有一定关系,有关甲状腺结节发生的影响因素尚待进一步研究。Objective To explore related risk factors of thyroid nodule in residents of Zhoushan Archipelago.Methods The residents were selected with random sampling and surveyed with a questionnaire and their thyroid conditions were assayed with B-mode ultrasound.The population-based case-control study was used to analyse the risk factors with logistic regression model.A total of 831 thyroid nodule cases were matched to 831 residents by gender,age,region,and occupation.Results The annual income was a protective factor for thyroid nodule（P =0.014,odds ratio = 0.875,95% confidence interval = 0.589-0.998）.Other factors such as dietetical conditions,iodine-salt intake,alcohol consumption,smoking,drinking tea,and the concentration of the urinary iodine had no significant correlation with thyroid nodule.Conclusion There is no close relation between thyroid nodule and dietary habits,the leveles of iodine nutrition in the residents of Zhoushan Archipelago.But futher study on influencing factors of thyroid nodule is needed.

关 键 词：甲状腺结节 危险因素 病例对照研究 海岛地区 

分 类 号：R541.8[医药卫生—心血管疾病]