缺血性修饰白蛋白在急性冠状动脉综合征早期诊断中的应用  

Values of Ischemia Modified Albumin in Early Diagnosis of Acute Coronary Syndrome

作　　者：代佳[1] 唐其柱[1] 邓伟[1] 周恒[1] 纵静[1] 

机构地区：[1]武汉大学人民医院心血管内科,武汉市430060

出　　处：《医药论坛杂志》2010年第12期1-2,5,共3页Journal of Medical Forum

摘　　要：目的通过对急性冠状动脉综合征(acute coronary syndromes,ACS)患者缺血性修饰白蛋白(ische-mia modified albumin,IMA)的研究,以探讨缺血修饰白蛋白(IMA)在急性冠脉综合征(ACS)早期诊断的临床价值。方法对我院103例ACS患者进行ECG检查,同时测定IMA、肌钙蛋白I(cTnI)和肌酸激酶同工酶MB(CK-MB)。并与同期32例门诊体检健康者进行对照。结果各组血清IMA水平(U/ml):正常组(74.38±3.96)U/ml,UA组(53.92±10.16)U/ml,AMI组(53.61±6.54)U/ml。UA组、AMI组与正常组(P<0.05)差异有统计学意义。结论 IMA可以作为心肌缺血早期敏感指标,提高ACS早期诊断。Objective To discuss the values of ischemia modified albumin in the early diagnosis of acute coronary syndromes.Methods One hundred and three patients with ACS were recorded ECG and tested IMA、cTnI and CK-MB.Thirty-two outpatient healthy subjects were served as normal controls.Results The IMA values in each group were as follows（U/ml）：The normal group（74.38±3.96）U/ml,UA group（53.92±10.16）U/ml,AMI group（53.61±6.54）U/ml,the difference is statistically significant.There were significant differences between UA group、AMI group and normal group（P0.05）.Conclusion Serum IMA was an early sensitive index,and it will improve the early diagnosis of acute coronary syndromes.

关 键 词：缺血性修饰白蛋白 急性冠状动脉综合征 早期诊断 肌钙蛋白I(cTnI) 肌酸激酶同工酶MB(CK-MB) ECG 

分 类 号：R541.4[医药卫生—心血管疾病]