血清TNF-α与早期自然流产关系的研究  

作　　者：李学文[1] 秦玲[1] 李雪莲[1] 

机构地区：[1]广州医学院附属深圳沙井医院妇产科,518104

出　　处：《中国社区医师（医学专业）》2010年第19期159-160,共2页

基　　金：深圳市宝安区科技局项目(编号2008287)

摘　　要：目的:研究早期自然流产(early spontaneous abortion,SA)妇女血清中TNF-α的表达水平,探讨其与自然流产的关系。方法:应用双抗夹ELISA法检测孕3月内20例正常妊娠、30例自然流产妇女血清中TNF-α的水平。结果:早期自然流产组与正常妊娠组比较,血清中TNF-α水平明显升高(P<0.05)。结论:TNF-α与早期自然流产的发生有关,其水平的升高与早期自然流产关系密切。Objective：To study the level of TNF-α（Tumor necrosis factor-α）in serum of the early spontaneous abortion.Methods：TNF-α were measured by sandwich-ELISA in 30 cases with the early spontaneous abortion,20 cases of normal pregnancies as the control.Results：The serum TNF-α of the early spontaneous abortion were significantly higher than those in the control group（P〈0.05）.Conclutions：The elevation express of TNF-α may be associated with oncogenesis of the early spontaneous abortion.

关 键 词：流产 肿瘤坏死因子 酶联免疫吸附测定 血清 

分 类 号：R442.2[医药卫生—诊断学]