A new twist in the microRNA pathway： Not Dicer but Argonaute is required for a microRNA production  

作　　者：Gabriel D Bosse Martin J Simard 

机构地区：[1]Laval University Cancer Research Centre, Hotel-Dieu de Quebec (CHUQ), Quebec City, Quebec G1R 2J6, Canada

出　　处：《Cell Research》2010年第7期735-737,共3页细胞研究（英文版）

摘　　要：Found in all metazoans, microRNAs or miRNAs are small non-coding RNA of-22 nucleotides in length that completely reshaped our understanding of gene regulation. This new class ofgene regulator is mostly transcribed by the RNA polymerase II producing a long stem-loop structure, called primary- or pri-miRNA, that will first be processed in the cell nucleus by a multiprotein complex called microprocessor to generate a shorter RNA structure called precursor- or pre-miRNA.

关 键 词：小RNA DICER 微RNA miRNA 英雄 生产 非编码RNA 小分子RNA 

分 类 号：Q522[生物学—生物化学] S511[农业科学—作物学]