2．5％碳酸氢钠溶液行口腔冲洗预防ICU呼吸机相关性肺炎的临床研究  

2.5 % sodium bicarbonate solution line oral prevention ICU ventilator- associated pneumonia

作　　者：张志兰[1] 苏冰连[1] 谢月霞[1] 李锦[1] 

机构地区：[1]广东省高州市人民医院外科ICO,525200

出　　处：《国际护理学杂志》2010年第7期965-967,共3页international journal of nursing

基　　金：茂名市科技计划研究基金项目（20092175）

摘　　要：目的探讨经口气管插管危重患者口腔护理方法，以减少口腔感染，减少口腔定植菌，切断胃-口腔-肺感染途径，减少呼吸机相关性肺炎。方法采用前瞻性队列研究，按随机数字将受试对象分实验组和对照组。实验组每天采用2．5％碳酸氢钠溶液行口腔擦洗加冲洗，每天3次，对照组用生理盐水棉球行口腔擦洗，两组均在口腔护理前后测定pH值，48h后行痰培养及口腔定植菌监测，分析两组患者呼吸机相关性肺炎（VAP）发生率、病原学检测结果。结果实验组呼吸机相关性肺炎发生率降低（P〈0．05），真菌感染率明显降低，121腔定植菌减少。结论采用2．5％碳酸氢钠溶液行1：3腔冲洗可有效减少口腔定植菌，降低呼吸机相关性肺炎发生率。Objective To discuss the effective oral nursing methods of critically ill patients with orotraeheal intubatton in order to reduce oral infection, reduce oral colonization, cut off the stomach - oral - pulmonary infection route, and reduce the number of ventilator - associated pneumonia. Methods Research methods for prospective cohort study. According to the random number will be subject, the eases were divided into experimental group and control group. Experimental group was given 2. 5% sodium bicarbonate solution line cleaning, washing and rinsing the oral cavity, three times a day. The control group was given normal saline llne cleaning, washing, cotton mouth. Two groups were made at the oral care before and after determination of the pH value after 48 hours. Sieksinus sputum culture and oral monitoring colonization were analyzed of two sets of ventilator - associated pneumonia （VAP） incidence.. Results The incidence of ventilator - associ- ated pneumonia in experimental group was reduced （ P 〈 0. 05 ）, and the fungal infection rate was significantly decreased.. Conclusions With 2. 5% sodium bicarbonate solution line of oral rinse can effectively reduce oral colonization and decrease the incidence of ventilator - as- sociated pneumonia.

关 键 词：经口气管插管 2.5%碳酸氢钠溶液 口腔冲洗 呼吸机相关性肺炎 

分 类 号：R473.5[医药卫生—护理学]