乌鲁木齐地区淋球菌、沙眼衣原体、溶脲脲原体感染情况调查  

Detection and analysis of Neisseria gonorrhoeae,Chlamydia trachomatis and Ureaplasma urealyticum infection in patients with urogenital tract infections in Urumqi,China

作　　者：阿曼古丽.牙生 李翠玲[2] 刘晓兰[3,4] 王红英[4] 田为真[4] 王灵[4] 庞楠楠[4] 马秀敏[4] 

机构地区：[1]新疆医科大学第一附属医院检验科,新疆乌鲁木齐830054 [2]新疆维吾尔自治区人民医院妇科 [3]石河子市人民医院妇科 [4]新疆医科大学基础医学院

出　　处：《中国病原生物学杂志》2010年第6期452-453,461,共3页Journal of Pathogen Biology

基　　金：教育部课题(No.Z2005-1-65003)

摘　　要：目的分析新疆乌鲁木齐地区淋球菌(Neisseria gonorrhoeae,NG)、溶脲脲原体(Ureaplasma urealyticum,UU)和沙眼衣原体(Chlamydiatrachomatis,CT)的感染情况。方法运用荧光定量PCR对乌鲁木齐地区316例疑似淋菌性/或非淋菌性尿道炎患者NG、CT和UU感染情况进行检测。结果 316例受检者NG感染率为21.2%,CT感染率为16.5%,UU感染率为24.7%,NG、CT、UU合计感染率为62.3%。男女、汉族和维吾尔族患者民族间NG、UU和CT感染率差异无统计学意义(P>0.05)。结论乌鲁木齐地区泌尿生殖道感染门诊患者中NG、CT和UU感染率较高;在检测NG、CT和UU方面,荧光定量PCR简便、快速,敏感性高、特异性强。Objective To detect and analyze urogenital tract infections of Neisseria gonorrhoeae（NG）,Chlamydia trachomatis（CT） and Ureaplasma urealyticum（UU） in Urumqi.Methods Three hundred and sixteen specimens from patients with a urogenital tract infection were tested for NG,CT,and UU using fluorescent quantitative PCR（FQ-PCR）.Results The overall rate of infection was 62.3%;the rate of infection with NG,CT,and UU was 21.2%（67/316）,16.5%（52/316）,and 24.7%（78/316）,respectively.There were no significant differences in the rate of NG,CT,and UU infection among the genders and the Uygur and Han ethnic groups.Conclusion Patients with urogenital tract infections in Urumqi had a high rate of infection with NG,CT,and UU.The FQ-PCR assay is easy to perform,quick,and able to detect NG,CT,and UU in urogenital tract infections with a high level of sensitivity and specificity.

关 键 词：淋球菌 沙眼衣原体 溶脲脲原体 荧光定量PCR 

分 类 号：R37[医药卫生—病原生物学]