PCI对左心室舒张或收缩功能的改善与冠状动脉病变严重程度的相关性研究  

Research of the relationship between left ventricular diastole function eft ventricular ejection fraction and severity of coronary artery lesions in CHD patients with PCI

作　　者：赵勇[1] 王彦[2] 李放[1] 付绍莉[1] 李玉兰[1] 王惠琴[1] 齐强[1] 刘丙木 周韦娜 李子志[1] 

机构地区：[1]河北省保定市第一中心医院,071000 [2]河北大学附属医院

出　　处：《河北医药》2010年第13期1699-1700,共2页Hebei Medical Journal

摘　　要：目的探讨成功经皮冠状动脉成形术(PCI)术前术后左心室舒张功能或收缩功能改善程度与冠状动脉病变严重程度的关系。方法对成功实施经皮冠状动脉成形术的冠状动脉粥样硬化性心脏病(CHD)住院患者112例,根据术前冠状动脉造影显示冠状动脉狭窄程度用累积积分法,分为高分组和低分组,术前及术后1个月行心脏超声检查,测量射血分数(EF),A峰、E峰及其比值,并进行比较。结果低分组、高分组术后EF值均明显高于术前(P<0.05或<0.01),且高分组术后EF值改善程度明显高于低分组(P<0.05),低分组、高分组术前术后E/A比值差异无统计学意义(P>0.05)。结论 CHD患者成功PCI后无论术前冠状动脉病变轻或重其左心室收缩功能都有明显改善,且对冠状动脉病变相对严重的患者左心室收缩功能改善更为明显。Objective To investigate the relationship between left ventriculardiastole function eft ventricular ejection fraction and the severity of coronary artery lesion in coronary heart disease （CHD） patients before and after PCI. Methods 122 patients who were treated with PCI were classified as high-score group （〉30） and low-score group（ 〈 30） according to the results of coronary angiography CAG,the left ventricular diastole function and left ventricular ejection fraction EF was analyzed before and after treatment with PCI for 1 month by Dappler echocardiography, and EF and E/F were measured. Results The levels of EF after treatment with PCI for 1 month in low-score group or high-score group were significantly higher than those before treatment with PCI （ P 〈0.01 or 〈0.05）. The degree of development of EF after treatment with PCI for 1 month in high- score group was higher than that in low-score group. However, there was no significant difference in E/A in low- score group or high-score group before and after PCI （ P 〉 0.05 ）. Conclusion The levels of left ventricular ejection fraction after PCI have obvious improvement whether the coronary artery lesions are severe or not before the operation,and the effect for the patients whose CHD is severer on the improvement of systolic function of left ventricle is more remarkable.

关 键 词：冠状动脉粥样硬化性心脏病 经皮冠状动脉成形术 左心室舒张功能 左心室收缩功能 冠状动脉狭窄 多普勒超声 

分 类 号：R541.4[医药卫生—心血管疾病]