注射hCG后不同时间行宫腔内人工受精对妊娠率的影响  

Effect of intrauterine insemination after injecting human chorionic gonadotropin at different times on pregnancy rate

作　　者：江梅 靳镭 徐婕[3] 聂睿[3] 彭芳昕[3] 

机构地区：[1]湖北省荆门市妇幼保健院妇产科,448000 [2]湖北省荆门市第二人民医院妇科 [3]华中科技大学同济医学院附属同济医院生殖中心

出　　处：《中国妇幼保健》2010年第19期2691-2694,共4页Maternal and Child Health Care of China

摘　　要：目的:探讨注射hCG后不同时间行宫腔内人工受精(Intrauter ineinsemination,IUI)对妊娠率的影响。方法:回顾性分析同济医院生殖中心472对夫妇实施IUI治疗的561个周期。根据注射hCG后行IUI的不同时间分为2组:hCG后24h IUI组和36h IUI组,比较两组IUI后的排卵时间及其对妊娠率的影响。结果:hCG后24h IUI359个周期和hCG后36h IUI202个周期的妊娠率分别为10.86%、10.89%,P>0.05,差异无统计学意义;两组24h内排卵的344个周期妊娠率为13.08%,明显高于24h内未排卵的217个周期妊娠率7.37%,P<0.05,差异有统计学意义。结论:影响IUI结局的因素并非注射hCG后IUI的时间,而是IUI后的排卵时间,距排卵时间越近妊娠率越高。阴道B超联合尿LH半定量试纸检测可以较准确预测排卵时间,有利于提高其周期妊娠率。Objective：To explore the effect of intrauterine insemination （IUI） after injecting human chorionic gonadotropin （hCG） at different times on pregnancy rate.Methods：561 IUI cycles from 472 couples in reproductive center of Tongji hospital were analyzed retrospectively and divided into 2 groups according to different times： 24 hours hCG IUI group and 36 hours hCG IUI group, the ovulation times and effects on pregnancy rate in the two groups were compared.Results：The pregnancy rates in 24 hours hCG IUI group （359 cycles） and 36 hours hCG IUI group （202 cycles） were 10.86% and 10.89%, respectively, there was no significant difference between the two groups （P0.05）; the pregnancy rate of 344 cycles （ovulation within 24 hours） was 13.08%, which was significantly higher than that of 217 cycles （non-ovulation within 24 hours） （P0.05）.Conclusion：The effect factor of IUI outcomes is ovulation time after IUI, not IUI time after hCG injection; the cases with shorter time from IUI to ovulation have higher pregnancy rate; vaginal type B ultrasound combined with urinary LH semiquantitative test paper detection may predict the ovulation time accurately, which is helpful to improve pregnancy rate per cycle.

关 键 词：宫腔内人工受精 妊娠率 HCG 

分 类 号：R711.6[医药卫生—妇产科学]