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作 者:黄垂学[1] 赵建农[1] 王鹏程[1] 刘健[1] 王宇田[1] 李俊驹[1]
机构地区:[1]海南省人民医院神经外科,海南海口570311
出 处:《海南医学院学报》2010年第7期867-868,877,共3页Journal of Hainan Medical University
基 金:海南医学院科研基金资助学报项目(0020100240)~~
摘 要:目的:观察星瑙灵对颅脑损伤患者头痛的临床疗效和安全性。方法:将148例颅脑损伤后头痛患者随机分为治疗组100例和对照组48例,所有患者均根据伤情进行神经外科常规治疗,治疗组在此基础上加用星瑙灵10mg,口服3次/d,共20d,进行治疗前、后疗效评定,比较治疗前、后肝、肾功能和心肌酶变化情况。结果:治疗组临床治愈率54.0%及总有效率85.0%明显高于对照组(25.0%、62.5%(P<0.05),而两组之间各项化验检查结果差异无显著性意义。结论:星瑙灵对颅脑损伤后头痛的疗效肯定,而且安全。Objective:To study the clinical effects and safety of oral Xingnaoling on headache resulted from craniocerebral injury.Methods:A total of 148 patients of craniocerebral injury were randomly divided into Xingnaoling-treatment group and control group.All patients received routine treatment according to their traumatic condition,and the treatment group took orally Xingnaoling 10 mg,tid×20 days.When the treatment completed,the clinical effects and serum ALT,T-BIL,Cr and CK levels were determined,then compared with the controll group.Results:The curative rate and total effective rate in treatment group were significantly higher than those in contoll group.However,there were no significant difference in the levels of serum ALT,T-BIL,Cr and CK between both groups.Conclusions:Xingnaoling is effective and safe on headache resulted from craniocerebral injury.
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