3种治法对流感病毒感染小鼠肺指数及肺指数抑制率的影响  

The Study of Effects on PulmonaryIndex and Pulmonary Index Inhibition Rate of Three therapies for Influenza Virus Infected Mice

作　　者：周坤福[1] 刘琳琳[1] 陆平成[1] 

机构地区：[1]南京中医药大学翰林学院,江苏南京210046

出　　处：《南京中医药大学学报》2010年第4期315-316,共2页Journal of Nanjing University of Traditional Chinese Medicine

摘　　要：目的通过观察清热解毒、宣肺化痰、养阴清肺3种治法对流感病毒感染小鼠肺指数、肺指数抑制率的影响,进一步验证3种治法治疗流感病毒性肺炎作用的有效性。方法选择3种治法的中药复方代表,并设利巴韦林为阳性对照,观察其对对流感病毒感染小鼠肺指数、肺指数抑制率的影响。结果3种治法均能降低流感病毒感染小鼠的肺指数,与模型组比较,有显著性差异(P<0.05,P<0.01)。结论3种治法均能减轻流感病毒感染小鼠引起的肺病变。OBJECTIVE To study effects on pulmonary index and pulmonary index inhibition rate of three therapies（heat-clearing and detoxicating remedy,releasing lung to dissipate phlegm,nourishing yin to clear away the lung-heat） for influenza virus infected mice,so as to explore the effectiveness of the three therapies in treatment of influenza viral pneumonia.METHOD Three representatives of herbal therapy were chosen.Ribavirin was set as the positive control,and effects on pulmonary Index and pulmonary index inhibition rate of the therapiesfor influenza virus infected mice were studied.RESULT Three therapies can decrease pulmonary index for influenza virus infected mice.CONCLUSION It showed that the three therapies could reduce ulmonary lesions caused by influenza virus infection in mice.

关 键 词：清热解毒法 宣肺化痰法 养阴清肺法 流感 肺指数 

分 类 号：R285.6[医药卫生—中药学]