难治性血小板减少性紫癜中医学四诊信息回顾性调查  

Retrospective Clinical Study on TCM Syndrome Features of Refractory Idiopathic Thrombocytopenic Purpura

作　　者：施怡[1] 李冬云[1] 陈信义[1] 

机构地区：[1]北京中医药大学东直门医院肿瘤血液科,北京100700

出　　处：《中国中医药信息杂志》2010年第7期28-30,40,共4页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：首都医学发展基金(SF-2005-031)

摘　　要：目的采用因子分析的方法,探讨难治性血小板减少性紫癜(RITP)中医临床证候特征,为中医药合理规范地治疗RITP提供思路。方法对75例RITP患者临床证候进行回顾性调查,统计患者症状、体征、舌脉的发生频率,并对发生频率在10%以上的症状或体征进行因子分析。结果气虚血瘀是RITP主要的证候类型,其代表症状为神疲乏力、气短、皮下紫斑、面唇紫黯、经血色黑有血块,代表舌脉为舌质黯淡、苔白,脉细弱或细涩;阴虚为其次的证候类型,代表症状为五心烦热、潮热盗汗、口干,代表舌脉为舌红少津、脉细数。结论气虚血瘀是RITP最主要中医证型,益气活血法为RITP最基本的中医治则。Objective To support a reasonable and standard TCM treatment principle for refractory idiopathic thrombocytopenic purpura （RITP） by exploring TCM syndrome features in RITP patients with factor analysis. Methods Seventy-five patients with RITP were studied retrospectively with their TCM syndrome features. The incidence rates of their various symptoms, body signs, tongue figures and pulse figures were calculated. The symptoms or body signs which incidence higher than 10% were analyzed by factor analysis. Results According to analysis and synthesis of tongue, pulse and symptoms, Qi deficiency and blood stasis was the major syndrome, of which the main signs were fatigue, shortness of breath, purple plague, dim complexion, dark menstrual blood, dark tongue body, write tongue coating, weak thready pulse or unsmooth thready pulse. And Yin deficiency was the secondary syndrome, of which main signs were burning sensation of five centers, hectic fever, night sweating, dry mouth, red tongue, shortness of tongue fluid and coating, rapid weak pulse. Conclusion For Qi deficiency and blood stasis being the major syndrome, one of TCM intervention treatment principles for RITP is invigorating Qi and promoting blood circulation.

关 键 词：难治性血小板减少性紫癜 中医证候 因子分析 回顾性调查 

分 类 号：R259.546.1[医药卫生—中西医结合] R241.2[医药卫生—中医内科学]