胺碘酮联合贝那普利对非瓣膜性房颤复律患者窦性心律维持和左心室收缩功能的影响  

Effect of Amiodarone Combined with Benazepril on the Maintenance of Sinus Rhythm and on the Left Ventricular Systolic Function of the Patients after Conversion of Non Valvular Atrial Fibrillation

作　　者：龚武田[1] 罗廷福[2] 

机构地区：[1]广元市第一人民医院心内科,四川硕士研究生628017 [2]双流县第二人民医院心内科,成都硕士研究生610213

出　　处：《西南军医》2010年第4期621-623,共3页Journal of Military Surgeon in Southwest China

摘　　要：目的探讨胺碘酮联合贝那普利对房颤复律后患者窦性心律维持和左心室收缩功能的影响。方法 68例房颤复律后的患者随机分为两组,对照组34例给予胺碘酮维持治疗,治疗组34例在对照组的基础上加用贝那普利,随访一年。维持治疗前和治疗后检测所有对象的心衰指标,统计各组房颤复发率。分析两组复发率及治疗前后心衰指标的差异。结果两组复发率差别有统计学意义,治疗组治疗前后,两组治疗后心衰指标有明显差异。结论胺碘酮联合贝那普利对房颤复律患者窦性心律的维持以及改善心功疗效优于单用胺碘酮。Objective To discuss the effect of amiodarone combined with benazepril on the maintenance of sinus rhythm and on the left ventricular systolic function of the patients after conversion of non valvular atrial fibrillation.Methods 68 cases after conversion of atrial fibrillation were randomly divided into 2 groups： treatment group and control group,34 cases in each;maintenance therapy with amiodarone was performed on patients in both groups while benazepril was added to patients in treatment group;follow-up lasted for 1 year;the heart failure index of patients in both groups were detected before and after treatment and the reoccurrence of atrial fibrillation was statistically studied;the reoccurrence and the differences of heart failure index before and after treatment were analyzed.Results The difference of the reoccurrence in the 2 groups was of statistical significance,and the heart failure index of the patients in treatment group before and after treatment were of obvious difference.Conclusions The combined treatment with amiodarone and benazepril both is of better effect than that with amiodarone only on the maintenance of sinus rhythm and heart function improvement in patients after conversion of atrial fibrillation.

关 键 词：胺碘酮 贝那普利 心房颤动 窦性心律 心功能 

分 类 号：R542.22[医药卫生—心血管疾病] R541.75[医药卫生—内科学]