贵阳市8097例乙肝五项标志物检测结果的调查报告  

作　　者：谢淼[1] 曾怡[1] 

机构地区：[1]武警贵州总队医院检验科,贵州贵阳550001

出　　处：《健康必读（下）》2010年第5期142-144,共3页

摘　　要：目的：为了解贵州省贵阳市普通健康体检人群的HbsAg携带率和抗-HBs水平状况，完善贵阳市乙肝免疫策略以及为防控方案提供支持。方法：收集武警贵州总医院和贵阳市妇幼保健院2009年1—11月体检人员乙肝五项的检测结果，对乙肝发病情况通过表格按年龄、性别分布进行统计，同时分析贵阳市17周岁以下儿童乙肝接种疫苗后阳性感染情况。用Excel2000建立数据库。用描述性分析的方法分析贵阳市2009年乙肝的流行病学特征及儿童乙肝疫苗预防效果。结果：HBsAg携带率为2．51％，单项抗-HBs阳性率为36．40％，HBV感染率为10．32％。贵阳市自1992年在0-14岁儿童中推广使用乙肝疫苗以来：17岁以下儿童HBsAg携带率只有0．39％，HBV感染率为0．71％．尤其0—7岁儿童HBsAg阳性率随年龄的减小而快速下降。〈17岁儿童的HBsAg阳性率高峰消失。〉17岁人群HBsAg阳性率呈缓慢上升趋势，说明普遍接种疫苗的显著预防效果。然而，年龄组HBsAg阳性率曲线高峰后移，且抗-HBs阳性率则呈波浪式变化，提示加强接种疫苗的重要性。接种乙肝疫苗是控制乙肝传播的有效措施，因此，建立并完善贵阳市乙肝免疫管理制度，不断巩固免疫成果，使人群抗体保持在较高的水平上，才是切实阻断HBV传播的关键所在。Objective：In order to understand and evaluate, the Guiyang City, Guizhou Province, general population health examination to bring the rate of HbsAg and anti--HBs levels of status, improve the Guiyang City, for the prevention and control of hepatitis B immunization strategies and programs to provide support. Methods： Collection of the CAPF Guizhou Hospital and Guiyang City, Maternal and Child Health Hospital in 2009 from January to December 5 medical personnel hepatitis B test results, the incidence of hepatitis B through the tables by age, gender distribution statistics, simultaneous analysis of Guiyang City, hepatitis B vaccination of children under 17 years of age vaccine--positive infection. To establish a database using Excel 2000. Descriptive analysis of Guiyang City in 2009 to analyze the epidemiological characteristics of hepatitis B and hepatitis B vaccine in children, preventive effect. Results： HBsAg carrier rate of 2.51%, anti -- HBs positive rate was 36.40%, HBV infection rate was 10.32%. Guiyang City in 1992, 0-14 year olds, has been promoting the use of hepatitis B vaccine： children under 17 years of age HBsAg carrier rate of only 0.39%, HBV infection rate was 0.71%. In particular, 0 -- 7--year--old HBsAg--positive rate for children age the decrease of rapid decline. ＂positive rate of 17--year--old children in the peak disappeared. ＂ 17--year--old HBsAg--positive rate of population was slowly rising trend, indicating a significant universal vaccination preventive effect. However, the age group, HBsAg--positive rate curve peak shift, and anti--HBs positive rate was wavy change, suggesting the importance of strengthening the vaccination, vaccinated with hepatitis B vaccine to control the spread of hepatitis B and effective measures, therefore, to establish and perfect the management system in Gulyang City, hepatitis B immunization, and constantly consolidate the immune results, so that the crowd Antibodies to maintain at a high level, should ef fectively block the spread of HBV key.

关 键 词：乙肝病毒 乙肝疫苗 感染率 感染模式 儿童免疫 

分 类 号：R512[医药卫生—内科学]