曲安奈德局部注射联合外用5%咪喹莫特治疗瘢痕疙瘩疗效观察  

Treatment on keloid with triamcinolone combined with 5% imiquimod cream

作　　者：赵建华[1] 乔少华[1] 耿文军[1] 付吉星[1] 

机构地区：[1]聊城市第二人民医院皮肤科,山东临清252601

出　　处：《中国美容医学》2010年第7期1053-1054,共2页Chinese Journal of Aesthetic Medicine

摘　　要：目的:观察曲安奈德局部注射联合外用5%咪喹莫特乳膏治疗瘢痕疙瘩的临床疗效。方法:将患者随机分为两组,治疗组给予曲安奈德局部注射治疗,每10～15天注射1次,2～3次为1个疗程,最多不超过3个疗程。同时外用5%咪喹莫特每周3次,连续外用3个月;对照组单纯给予曲安奈德注射液局部注射治疗。治疗结束后随访1年,判断疗效并观察复发情况。结果:治疗组有效率96.4%,明显优于对照组(P<0.05),差异有显著性意义。治疗组复发率低于对照组。结论:曲安奈德局部注射联合外用5%咪喹莫特乳膏治疗瘢痕疙瘩治愈率高,疗效确切。Objective To observe the efficacy of triamcinolone combined with 5% imiquimod cream in the treatment on keloid.Methods Patients were randomly divided into two groups.The treatment group orally took injection of triamcinolone one time every 10 ～15 days and 2 ～3 times a course for no more than 3 courses.The same time the treatment group took 5% imiquimod cream for three months.The control group only took injection of triamcinolone.one year after finishing the treatment,the evaluation of the efficacy and drug with drawal,follow-up recurrence of the situation was carried out.Results After one year,effective in the treatment （96.4%） was significantly higher than that in control group （P〈0.05）.The rate of relapse in control group was significantly higher than that in the treatment group.Conclusion Triamcinolone combined with 5% imiquimod cream in the treatment on keloid have a more satisfactory effect.

关 键 词：曲安奈德 5%咪喹莫特 瘢痕疙瘩 

分 类 号：R619.6[医药卫生—外科学]