新型工业杀菌剂异噻唑啉酮类包合物的合成研究  

A Novel Industry Bactericide—Synthesis of Isothiazolinone Clathrate

作　　者：李淑琏[1] 谭小青[1] 

机构地区：[1]华南师范大学化学系

出　　处：《精细化工》1999年第1期4-7,共4页Fine Chemicals

摘　　要：以丙烯酸甲酯为起始原料，经硫化、胺解、氯环化三步得到５氯２正辛基４异噻唑啉３酮，总收率１６７％。以双酚Ｆ为主体，上述异噻唑啉酮为客体，质量比为４∶１，形成分子包合物。产物结构经ＩＲ、１ＨＮＭＲ确认，对７种微生物试验，其抑菌能力比同类产品ＧａｔｈｏｎＣＧ大５～１０倍。The novel industry bactericide is a clathrate which is composed of 5 chloro 2 n octyl 4 isothiazolin 3 one and 4,4′ dihydroxydiphenylmethane.A reasonable synthesis route of first compound has been given out in this paper.It includes sulfidation,aminolysis and chloro cyclization,total yield is 16.7%.The product has identified by IR and 1 HNMR.The clathrate obtained is more effective in bactericidal potency than the same kind bactericide Gathon C G.

关 键 词：异噻唑啉酮 双酚F 杀菌剂 农药 有机杀菌剂 

分 类 号：TQ455.47[化学工程—农药化工]