磁性琼脂糖复合微球的制备和性质  

Preparation and Characterization of Magnetic Agarose Composite Microspheres

作　　者：邱广亮[1] 栗淑媛[1] 金志兰 刘春艳 

机构地区：[1]内蒙古师范大学生物系

出　　处：《精细化工》1999年第1期38-41,共4页Fine Chemicals

基　　金：内蒙古自然科学基金;教育厅高校研究资助项目

摘　　要：采用乳化复合技术制备出粒径为２０～３００ｎｍ、分散系数为０．０９０～０．６０１、Ｆｅ３Ｏ４含量（ｗ）为７．５％～６１．３％的具有磁核的琼脂糖复合微球。该微球呈珠形，在４～９０℃的水介质中形成均匀稳定的分散液，在０．０５Ｗｂ／ｍ２的弱磁场中具强磁响应性。制备微球的最佳条件是：琼脂糖用量１２．５～８７．５ｍｇ／ｍｌ，氯化亚铁用量１５～１２０ｍｇ／ｍｌ，ｐＨ＞１０。The magnetic agarose composite microspheres have been prepared by precipitation of magnetite from the mixture of ferrous ions and hydrogen peroxide in the prensence of agarose and sodium hydroxide.The microspheres,containing magnetite cores surrounded by chemisorbed agarose,have 20～300nm diameter with being distributed.They have good magnetic responsibility in the presence of magnetic field and good dispersion stability in water.Experimental results have indicated that,agarose,pH value of solution and FeCl 2 have the great effects on forming magnetic agarose composite microspheres.The optimum conditions are as follows:the mass concentrations of agarose and ferrous chloride are 12.5～87.5 mg/ml and 15～120mg/ml respectively,pH value of solution equals 10.

关 键 词：磁性 氧化铁 琼脂糖 磁性复合微球 乳化 磁粉 

分 类 号：TQ586.1[化学工程—精细化工] O629.12[理学—有机化学]