素食膳食对动脉粥样硬化危险因素的影响  

Effect of vegetarian diet on the risk factors for arteriosclerosis

作　　者：李学军[1,2] 闫冰[2] 刘长勤[2] 石秀林[2] 王丽英[2] 张惠杰[2] 余亚信[2] 杨叔禹[2] 张素华[1] 

机构地区：[1]重庆医科大学附属第一医院内分泌科,重庆400016 [2]厦门大学附属第一医院糖尿病科厦门市糖尿病研究所,厦门361003

出　　处：《中国实用内科杂志》2010年第7期631-633,共3页Chinese Journal of Practical Internal Medicine

基　　金：厦门市科技局资助项目(3502Z20071105);厦门市卫生局科研资助项目(WSK0501)

摘　　要：目的探讨素食膳食方式对动脉粥样硬化的影响。方法选取健康的普食者268名和388名健康的素食者进行横断面研究。采集受试者的基本情况、素食史、生活习惯、血压、人口学资料,采肘静脉血测定空腹血糖(FBG)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A1(Apo-A1)和载脂蛋白B(Apo-B)、游离脂肪酸(FFA)、同型半胱氨酸(Hcy)、超敏C-反应蛋白(hsCRP)、脂联素(APN)、以及肝肾功等生化指标。结果素食组血压、体重指数、TC、TG、DL-C、LDL-C、Apo-A1、Apo-B、FFA、Hcy、γ-谷氨酰转肽酶(γ-GT)、血尿酸(UA)、空腹血糖(FBG)等均低于普食组(P<0.05);而碱性磷酸酶(ALP)、HDL-C与TC的比值、以及脂联素(APN)则显著高于普食组(P<0.05或P<0.001)。结论素食膳食方式可影响致动脉粥样硬化的危险因素,对防治动脉粥样硬化性疾病具有积极的作用。Objective To investigate the effect of vegetarian diet on the arteriosclerosis. Methods The subjects included 268 healthy omnivores and 388 healthy lacto vegetarians. The general information, history of vegetarian diet,living habit, blood pressure and data of population of subjects were collected. Meanwhile, each volunteer were detected blood biochemical indicators, including fasting blood glucose （FBG）, total cholesterol （TC）, triglyceride （TG）, high density lipoprotein cholesterol （HDL-C）, low density lipoprotein cholesterol （LDL-C）, apo lipoprotein A1 （ ApoA1 ） and apo lipoprotein B （ ApoB ） ; free fatty acid （ FFA）, homocystine （ Hcy）, γ-glutamyt transpeptidase （γ-GT）, high sensitivity c reactive protein （hsCRP）, adiponectin （APN）, blood uric acid （BUA） ,liver function and renal function. Results The levels of blood pressure, body mass index （ BMI）, TC, TG, HDL-C, LDL-C, Apo-A1 , Apo-B, FFA, Hcy, γ-GT, BUA and FBG were significantly lower in lacto vegetarians than in omnivores （ P 〈 0. 05 ）. And the alkali phosphatase, HDL-C/TC, APN were obviously higher in lacto vegetarians than in omnivores （P 〈 0. 05 or P 〈0. 001 ）. Conclusion Lacto vegetarian influences the risk factors for arteriosclerosis and has positive effects on prevention and cure of arteriosclerosis.

关 键 词：素食膳食 生活方式 血压 血脂 

分 类 号：R5[医药卫生—内科学]