丙型肝炎病毒感染慢性化趋势危险因素的流行病学研究  

An epidemiological study on the risk factors of chronic tendency for HCV infection

作　　者：阚晓宏 倪进发[2] 毕鹏[2] 孙业桓[2] 程慧[2] 郑惠珍[2] 黄守凯[2] 张庶民[3] 

机构地区：[1]安徽省结核病防治研究所,230022 [2]安徽医科大学 [3]中国药品生物制品检定所

出　　处：《河南预防医学杂志》1999年第1期5-7,共3页Henan Journal of Preventive Medicine

摘　　要：为探索丙型肝炎病毒感染慢性化危险因素，我们调查了安徽省某乡“职业”献血员与两所省级医院传染科住院病例中，抗-HCV（＋）和/或HCVRNA（＋）者共142例，其中病例组76例，对照组66例。结果显示病例组有饮酒习惯的比例明显高于对照组（x2＝8．75，P＜0．003，OR＝2．79），饮酒量与慢性丙型肝炎呈相关关系;持续饮酒≤5年，OR＝1．74，6－15年OR＝3．51；＞15年OR＝5．10；两组间经血传播与非经血传播比例差异显著（x2=4．859，P＜0．05），病例组有经血传播史的比例是对照组的5．10倍，本研究HCV血清学分型、吸烟、饮食习慢等，两组间差异不显著，ln order to analysis the risk factors of chronic tendency of HCV infection, 142 cases of HC were collected, Among these the HC cases group were defined as disease courses were over b Months, albuinin/globulin< 1.5 and/ir ALT>40 units,others be defined as control group. Being compared the risk factors of both group,it was showed that the drinking habit were positive association with chronic HC. The more increasing the amountof drinking each time and being continuanced,The more the chronic tendency.So drinkibng is the mostimportant fisk factor.There were also show that blood and non blood transfusion were difference significantly. The former were 5.10 fold than later in HC chronic tende ncy. HCV seritype,HCV genotype,smoking,style for foodtaking,etc. were no difference in the two groups.

关 键 词：慢性 危险因素 丙型肝炎 流行病学 

分 类 号：R512.630.1[医药卫生—内科学]