血糖浓度和血红蛋白释放试验的比对研究  

Comparative study on the blood glucose concentration and Hemoglobin Release Test

作　　者：张晓燕[1] 高丽君[2] 高雅琼[2] 周立社[2] 苏燕[2] 秦良谊[2] 秦文斌[2] 

机构地区：[1]内蒙古自治区包头医学院附属第二医院检验科,014030 [2]内蒙古自治区包头医学院血红蛋白研究室,014010

出　　处：《国际检验医学杂志》2010年第6期524-525,共2页International Journal of Laboratory Medicine

基　　金：内蒙古自治区教育厅重点科研项目(NJ 09157)

摘　　要：目的探讨血红蛋白释放试验(HRT)与糖尿病的关系,观察血糖浓度对HRT的影响。方法取各种血糖浓度的血液标本,每例标本同时做全血和红细胞的HRT(应用梯带释放法),观察血糖浓度与HRT结果的关系。进一步进行体外试验,以研究葡萄糖对HRT的影响。结果全血HRT结果与血糖浓度无关。梯带释放与血糖浓度有一定的相关性。体外试验葡萄糖浓度对红细胞的梯带释放影响明显;葡萄糖能使梯带增强,且有按5%、10%、50%递增趋势。结论葡萄糖能影响红细胞的HRT,改变红细胞的通透性。Objective To explore the relationship between hemoglobin release test（HRT）and diabetes,and to know the effect of blood glucose on HRT.Methods 10 blood samples was take to do whole blood HRT and erythrocyte HRT（ladder release）simultaneously,analysis the relationship between the concentration of blood glucose and results of HRT.In vitro,the effect of blood glucose on HRT was studied.Results There did not exist relationship between whole blood HRT and blood glucose concentratlon. But Iadder release was associated with blood glucose concentration.In vitro,glucose concentration influenced the ladder release of erythrocyte.Glucose enhanced the ladder release with the trend of 5%、10%、50%.Conclusion Glucose could influence the erythrocyte HRT with changing the permeability of erythrocyte.

关 键 词：血糖 血红蛋白类 红细胞 对比研究 

分 类 号：R446.12[医药卫生—诊断学]