经皮冠状动脉腔内成形术对心率变异性的影响  

Effect of percutaneous transluminal coronary angioplasty on cardiac autonomic nervous function.

作　　者：陈柯萍[1,2] 尹彦琳[1,2] 吴永健[1,2] 王方正[1,2] 陈新[1,2] 

机构地区：[1]中国医学科学院阜外心血管病医院电生理研究室 [2]中国协和医科大学心血管病研究所

出　　处：《临床心电学杂志》1999年第1期26-28,共3页Journal of Clinical Electrocardiology

摘　　要：目的本文对２２例行经皮冠状动脉腔内成形术（ＰＴＣＡ）的患者进行２４小时心率变异性（ＨＲＶ）检查，以了解ＰＴＣＡ对心率变异性的影响。方法所有患者均于ＰＴＣＡ术前进行２４小时Ｈｏｌｔｅｒ记录，并于术后１周及３个月重复检查，ＨＲＶ检查方法包括时域分析（ＳＤＮＮ、ＳＤＡＮＮ和ＳＤＮＮ指数）和频域分析（ＴＦ、ＬＦ和ＨＦ）。结果ＰＴＣＡ术后１周ＨＲＶ值较术前降低。其中时域指标：ＳＤＮＮ、ＳＤＡＮＮ和ＳＤＮＮ指数明显降低（Ｐ＜０．０５）。频域指标：ＴＦ、ＬＦ和ＨＦ亦明显降低（Ｐ＜０．０５）。术后３个月复查，ＨＲＶ恢复至术前水平。结论ＰＴＣＡ术后１周ＨＲＶ明显下降，但这种早期的自主神经功能损伤是暂时的。Objective The purpose of this study was to determine the influences of percutaneous transluminal coronary angioplasty (PTCA) on heart rate variability(HRV).Methods Three-channel,24-hour ambulatory ECG were performed.Time and frequency domain measures of HRV were analyzed from 24-hour ambulatory electrocardiagraphic recordings.HRV was performed before PTCA and repeated at a week and 3 months after PTCA.Results Compared with the values of HRV before PTCA,time domain analysis at one week after PTCA revealed a significant decrease in SDNN,SDANN and SDNN index( P <0 05)and frequency domain analysis revealed marked attenuation of totle,low and high frequency components( P <0 05).All values could improved at three months after PTCA.Conclusion These data suggest that autonomic nervous system activity may beimpaired early after PTCA but could recovered.

关 键 词：PTCA 心率变异性 自主神经功能 冠心病 

分 类 号：R654.2[医药卫生—外科学]