前列舒康胶囊对前列腺炎模型大鼠及前列腺组织形态的影响  

Effect of Qianlie Shukang Capsule on Pathomorphology of Prostate and the Tissues of Prostatitis in Model Rats

作　　者：赵富虎 刘丽春[2] 滕宝霞[3] 

机构地区：[1]兰州太宝制药有限公司,兰州730050 [2]甘肃省人民医院,兰州730000 [3]甘肃省药品检验所,兰州730000

出　　处：《中国实验方剂学杂志》2010年第8期189-192,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:考察前列舒康胶囊对消痔灵和大肠杆菌所致大鼠前列腺炎的影响。方法:采用文献方法造模,连续给药30d后观察大鼠前列腺湿重、前列腺白细胞及卵磷脂小体密度,并进行统计学处理。结果:前列舒康胶囊各剂量组可明显降低模型大鼠前列腺质量和白细胞数(P<0.01),中、高剂量组可回升低下的卵磷脂小体密度(P<0.05或P<0.01),明显降低大鼠前列腺组织中炎细胞浸润和成纤维细胞增生(P<0.05)。结论:前列舒康胶囊可显著改善慢性前列腺炎病组织学的异常改变;对大肠杆菌所致细菌性前列腺炎具有显著的治疗作用。Objective：To investigate the effects of Qianlie Shukang Capsule in treating prostatitis.Method：Pharmacological investigations were carried out to study the impact of Qianlie Shukang Capsule on rat＇s prostate fribrosis inflammation caused by Xiaozhiling and on rat＇s prostatitis caused by Escherichia coli.Result：Qianlie Shukang Capsule has significant effect for treating prostatitis induced by Xiaozhiling and that induced by E.coli,indicated by prostate weight,leucocyte count and lecithin density （P〈0.05 or P〈0.01 ）.Conclusion：Qianlie Shukang Capsule can alleviate prostate pathological changes in chronic prostatitis,and is effective in treating bacterial prostatitis incause by E.coli.

关 键 词：前列舒康胶囊 前列腺炎 大鼠模型 

分 类 号：R285.5[医药卫生—中药学]