新型丝攻结合骨水泥强化椎弓根螺钉固定的体外生物力学研究  

Biomechanical study on strengthening pedicle screw fixation using a novel tap with bone cement in vitro

作　　者：刘达[1] 雷伟[1] 吴子祥[1] 高明暄[1] 万世勇[1] 石磊[1] 李丹[1] 吕荣[1] 

机构地区：[1]第四军医大学西京医院全军骨科研究所,陕西西安710032

出　　处：《中国现代医学杂志》2010年第12期1785-1788,共4页China Journal of Modern Medicine

基　　金：国家高技术研究发展计划(863计划)(No:2007AA02Z468)

摘　　要：目的评价新型丝攻结合骨水泥(PMMA)增强椎弓根螺钉稳定性的效果。方法选取34个新鲜小牛腰椎,每个椎体的一侧椎弓根直接拧入螺钉(空白组);另一侧将PMMA(2.0mL)经新型丝攻注入钉道后拧入螺钉(实验组)。24h后行轴向拔出实验和周期抗屈实验。结果实验组中螺钉的最大轴向拔出力和能量吸收值均显著高于空白组(P<0.05);实验组中的螺钉能够耐受更大的负荷或者在同等负荷下产生较小的位移。结论新型丝攻结合PMMA可以显著增加椎弓根螺钉固定的稳定性。【Objective】To evaluate the effect of strengthening pedicle screw fixation using a novel tap with polymethylmethacrylate （PMMA） in vitro.【Methods】34 fresh adult goat lumbar vertebrae were harvested. The track in every pedicle was prepared by the same tap and method. Before insertion of screw, no screw augmentation was performed to one side of each lumbar vertebrae （blank group）, and PMMA （2.0 mL） was injected into bone around the track in the other side （experiment group）. 10 lumbar vertebrae were selected randomly followed by axial pullout test and periodical bending resistance test was performed to the other 24 lumbar vertebrae 24 hours after the fixation. 【Results】The maximum axial pullout strength and energy absorption value in experiment group were significant higher than those in blank group, respectively （P 0.05）. The screws in experiment group received more loading or reduce fewer shifts under the same loadings compared with screws in blank group in periodical bending resistance test. 【Conclusions】Using a novel tap with PMMA can significantly strengthen the stability of pedicle screw fixation and provide a novel method to solve loosing of screws in clinic. It has a favorable perspective in clinical application.

关 键 词：椎弓根螺钉 骨水泥 最大轴向拔出力 能量吸收值 生物力学 

分 类 号：R318.01[医药卫生—生物医学工程]