内镜下逆行胰胆管造影后胰腺炎危险因素的多因素分析  

Multivariate analysis of risk factors for post-ERCP pancreatitis

作　　者：张春[1] 王立新[1] 徐智[1] 侯纯升[1] 凌晓峰[1] 周孝思[1] 

机构地区：[1]北京大学第三医院普通外科,北京100191

出　　处：《中国内镜杂志》2010年第6期564-567,共4页China Journal of Endoscopy

摘　　要：目的对住院患者内镜下逆行胰胆管造影后胰腺炎(PEP)进行回顾性研究,分析PEP的危险因素,提出适合实际情况的预防措施。方法 2006年1月～2007年12月,该院住院行内镜下逆行胰胆管造影(ER-CP)305次。以PEP为因变量,以16个患者因素、17个医源因素为自变量进行统计分析,并行Logistic回归多因素分析,找出PEP的独立危险因素。结果 305次患者中,51次发生PEP(16.7%)。单因素分析显示,胰管显影与PEP密切相关。结论胰管显影是PEP的危险因素,术前使用胰酶抑制剂不能降低PEP风险。[Objective]The aim of this study is to analyze the risk factors for post-ERCP pancreatitis in our cases and find measures of prevention. [Methods]Data of consecutive 305 patients, who have undergone ERCP at Peking University Third Hospital from January 2006 to December 2007, were enrolled in the study to analyze the in-hospital morbidity. Dependent variable was in-hospital morbidity, whereas the independent variables included 16 patient-related and 17 procedure-related risk factors. Logistic regression analysis was used to find the risk factors for PEP. [Results]In 305 patients, morbidity rate of PEP was 16.7% . PEP was associated with the risk of pancreatic duct imaging.[Conclusions]Pancreatic duct injection is the risk factor of PEP. Trypsin inhibitor can not be used before surgery to reduce the risk of PEP.

关 键 词：胰腺炎 内镜下逆行胰胆管造影 危险因素 

分 类 号：R657.51[医药卫生—外科学]