七氟烷和肌松药用于小儿气管支气管异物取出术的临床研究  

Clinical investigation of application of Sevoflurane and muscle relaxant to foreign body extraction in respiratory tract of infants

作　　者：童易如[1] 张溪英[1] 颜璐璐[1] 邝日裕[1] 周星星[1] 

机构地区：[1]湖南省儿童医院麻醉科,湖南长沙410007

出　　处：《中国内镜杂志》2010年第6期632-634,共3页China Journal of Endoscopy

摘　　要：目的比较维库溴铵、小剂量维库溴铵、七氟烷复合更小剂量维库溴铵用于小儿气管支气管异物取出术的优缺点。方法 5个月到7岁10个月择期行气管异物取出术患儿60例,随机分为W1组(维库溴铵0.1mg/kg)、W2组(维库溴铵0.05mg/kg)、W3组(七氟烷+维库溴铵0.04mg/kg)。记录手术时间、麻醉恢复时间、给药3min仍有肢动或呼吸动作人数、气道不良反应(呛咳、屏气、喉痉挛)。结果 3组手术时间无明显区别,麻醉恢复时间W1组>W2组>W3组,W1、W3组给药后肌松良好,W2组有30%患儿给药3min后仍有肢动或呼吸动作,3组均无气道不良反应。结论七氟烷复合0.04mg/kg维库溴铵用于小儿气管支气管异物取出术是一种安全的麻醉方法 。[Objective]To compare the advantages and disadvantages of anesthesia by vecuronium, small dose vecuronium, sevoflurane and smaller dose vecuronium in the anesthesia of tracheobronchial foreign body extraction in infants. [Methods]Sixty children aged from 5 months to 7 years and 10 months who were performed tracheobronchial foreign body extraction were randomly allocated to three groups： group W1 （Vecuronium 0.1 mg/kg）, group W2 （Vecuronium 0.05 mg/kg）, group W3 （Sevoflurane＋Vecuronium 0.04 mg/kg）. The time of operation and recovery, the number of body move or breathe action 3 min after administration, the adverse reaction of airway （such as bucking, breathholding, laryngismus） were recorded.[Results]There is no significant difference of the operation time between the three groups, the time of recovery： W1W2W3, the patients of group W1, group W2 were well relaxant after administration, but there are 30% patients still had body move or breathe action 3 min after administration. There was no adverse reaction in the three groups. [Conclusions]The application of sevoflurane and vecuronium to tracheobronchial foreign body extraction in infants is safety.

关 键 词：小儿气管支气管异物 维库溴铵 七氟烷 麻醉 

分 类 号：R614[医药卫生—麻醉学]