噬菌体制剂的研究现状及发展前景  

Recent Advances and Prospects in Bacteriophage Therapy

作　　者：赵庆友[1] 朱瑞良[1] 

机构地区：[1]山东农业大学动物科技学院,山东泰安271018

出　　处：《中国兽药杂志》2010年第7期40-43,共4页Chinese Journal of Veterinary Drug

基　　金：高等学校博士学科点专项科研基金(060434011);山东省优秀中青年科学家科研奖励基金(03BS140);山东省科技攻关项目(2008GG10009023)

摘　　要：噬菌体制剂是利用噬菌体溶解细胞的特性而用于治疗动物的病原菌的临床感染。早在20世纪初,噬菌体治疗就取得了积极的治疗效果。目前传统抗生素治疗动物细菌感染时易产生耐药性,而噬菌体制剂则表现出许多突出的优越性。从噬菌体的生物学特性,噬菌体制剂的作用机制,以及噬菌体制剂的发展状况和应用前景等方面进行了论述。Phage therapy is treated bacterial clinical infections of animals with bacteriolysis.In the 1920＇s,phage therapy had efficiency in clinical treatment.Many creatural experiments and clinical treatments indicate that phage therapy is a potential alternative method for treatment and prevention of bacteria disease.This method comes along,quite opportunely to counter the resistance problem of the antibiotics.From the biological characteristics,the therapy mechanism,the development status and the application prospects,the systemic discussion of bacteriophage in this paper.

关 键 词：噬菌体 制剂 应用 现状 前景 

分 类 号：Q785[生物学—分子生物学]