去甲肾上腺素和多巴胺对感染性休克复苏效果的对比研究  

Comparison evaluation of resuscitation effect of norepinephrine and dopamine on the treatment of septic shock

作　　者：刘鹏[1] 陈童恩[1] 张玉楚[1] 杨群[1] 陈培服[1] 胡旭军 许兆军[1] 

机构地区：[1]宁波市第二医院重症监护室,浙江宁波315010

出　　处：《全科医学临床与教育》2010年第3期265-267,共3页Clinical Education of General Practice

摘　　要：目的比较去甲肾上腺素和多巴胺对感染性休克的复苏效果。方法将50例感染性休克患者随机分为观察组和对照组各25例,观察组采用去甲肾上腺素治疗,对照组应用多巴胺治疗,比较分析两组的复苏效果。结果观察组的复苏率为80.00%,对照组为52.00%,两组间差异有统计学意义(χ2=4.36,P<0.05);且观察组12h、24h的乳酸清除率高于对照组,两组间差异有统计学意义(t分别=5.17、5.09,P均<0.05)。结论去甲肾上腺素治疗感染性休克疗效较佳,患者复苏达标率高。Objective To compare the resuscitation effect of norepinephrine and dopamine on the treatment of septic shock. Methods Fifty patients of septic shock were randomly divided into observation group （25 cases） and control group （25 cases） according to the order of hospitalization. The observation group were treated by norepinephrine and the control group were treated by dopamine. The resuscitation effects of two groups were compared and analyzed. Results The resuscitation success rate in observation group was 80.00% and that in the control group was 52.00% and there was a significant difference between the two groups （χ2=4.36,P〈0.05）. The lactate clearance rates at 12 hours and 24 hours of the observation group were higher than that of the control group with significant differences （t=5.17,5.09,P〈0.05）. Conclusions Norepinephrine has better efficacy than dopamine in the treatment of septic shock; its resuscitation success rate is higher.

关 键 词：感染性休克 去甲肾上腺素 多巴胺 复苏 

分 类 号：R459.7[医药卫生—急诊医学]