8羟-基喹啉铜配合物催化甲苯与H_2O_2的选择羟基化反应  

Selective Hydroxylation of Toluene with Hydrogen Peroxide Catalyzed by 8-Quinolinolato Copper(Ⅱ)Complexes

作　　者：卢春丽[1] 伏再辉[1] 刘凤兰[1] 秦金伟[1] 何乡陵[1] 尹笃林[1] 

机构地区：[1]湖南师范大学化学化工学院精细催化合成研究所,中国长沙410081

出　　处：《湖南师范大学自然科学学报》2010年第2期72-76,共5页Journal of Natural Science of Hunan Normal University

基　　金：国家自然科学基金资助项目(20873040;20573035)

摘　　要：设计合成了一系列四齿8-羟基喹啉铜配合物(Q2CuⅡ),发现这些铜配合物能有效催化双氧水选择氧化甲苯反应,主要获得芳环上的羟基化产物邻和对甲酚(选择性约80%).Q2CuⅡ配合物的取代基对催化活性有明显影响,其中2,8-二羟基喹啉铜显示最好的活性,通过优化反应条件如反应温度、催化剂、氧化剂用量以及乙腈和水的体积比,获得了20.6%的甲苯转化率和80%甲酚选择性.基于液体紫外对反应的监控结果,推测了Q2CuⅡ催化双氧水氧化甲苯的机理.A series of 8-quinolinolato copper（Ⅱ） complexes（Q2CuⅡ） have been synthesized and characterized by IR and UV-Vis spectrocopy.These Q2CuⅡ catalysts were found to be active and selective for the oxidation of toluene with aqueous hydrogen peroxide（H2O2） in the presence of acetonitrile/water（1∶1） at 70 ℃,mainly affording a highly hydroxylated products o-and p-cresols with an approximate selectivity of 80%.Among the Q2CuⅡ catalysts examined,the 2,8-dihydroxyl-Q2CuⅡ showed the best activity with the toluene conversion of 20.6 %.The effect of amount of catalyst,reaction temperature and ratio of acetonitrile/water on this oxidation process were also investigated.Based on the UV-Vis characterization,a possible mechanism for the Q2CuⅡ catalytic system was also proposed.

关 键 词：8羟-基喹啉铜 选择性氧化 双氧水 甲苯 甲酚 

分 类 号：O643[理学—物理化学]