Fenwal CS3000plus血细胞分离机自体与异体外周血造血干细胞采集效率比较  

Comparison of the efficiency of Fenwal CS 3000 plus blood cell separators in collecting autologous and allogeneic peripheral blood stem cells

作　　者：张根玲[1] 苗莹莹[1] 赵敏[1] 李忠俊[1] 

机构地区：[1]第三军医大学新桥医院输血科,重庆400037

出　　处：《重庆医学》2010年第14期1844-1845,共2页Chongqing medicine

摘　　要：目的比较分析应用Fenwal CS3000plus血细胞分离机采集自体与异体外周血造血干细胞后有核细胞(MNC)采集效率。方法抽样分析外周血造血干细胞190例次采集样本,其中自体采集109例次,异体采集81例次。比较两组采集产品中单个核细胞数占采集前自身单个核细胞总数的百分比。结果两组采集效率比较,差异有统计学意义(P≤0.001),采集MNC效率与采集前外周血MNC总数均呈负相关。结论自体外周血造血干细胞采集效率优于异体造血干细胞的采集效率。Objective To compare the MNC collection efficiency of Fenwal CS 3000 Plus Blood Cell Separators in collecting autologous and allogeneic peripheral blood stem cells.Methods 190 peripheral blood stem cell samples were collected,of which 109 cases were autologous collection,81 cases were allogeneic collection.The percentage of the mononuclear cells in total autologous mononuclear cells before collected of the two collections was compared.Results The collection efficiency of two groups were variable（P≤0.001）,and the MNC collection efficiency is negative correlation with the sum total of peripheral hematopoietic.Conclusion The collection efficiency of outo-hematopoietic stem cell transplantation patients was superior than that of allo-hematopoietic stem cell transplantation patients.

关 键 词：造血干细胞 白血病 

分 类 号：R457[医药卫生—治疗学]