腰池持续引流联合高压氧对重型颅脑损伤术后并发慢性脑积水的影响  

Effects of continuous lumbar drainage combined with hyperbaric oxygen on the postoperative chronic hydrocephalus of severe craniocerebral injury

作　　者：段军伟 唐晓平 王远传 罗仁国 漆建 唐文国 张涛 彭华 李舜 梅才君 陈灵 

机构地区：[1]川北学院附属医院神经外科,四川南充637000

出　　处：《中华航海医学与高气压医学杂志》2010年第3期133-135,共3页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

基　　金：基金项目：四川省医学重点学科及重点专科建设项目资助（川卫办发[2007]407号）;四川省卫生厅科研项目资助（070301）

摘　　要：目的 探讨重型颅脑损伤（severe craniocerebral injury,SCI）术后早期行腰池持续引流（continuous lumbar drainage,CLD）联合高压氧（hyperbaric oxygen,HBO）治疗对患者慢性脑积水（chronic hydrocephalus,CH）的影响.方法 将我院390例SCI术后患者分为3组：A组130例早期HBO联合CLD治疗,B组130例CLD治疗,C组130例常规药物治疗.比较1年内患者发生CH的差异.结果 3组病例1年内发生CH的比例（例数）分别为：A组5.38%（7例）,B组12.31%（16例）,C组21.54%（28例）,采用x2检验比较3组发病率差异性,A、B组比较x2=3.864,P〈0.05;B、C组比较x2=3.939,P〈0.05;A、C组比较x2=14.560,P〈0.01.结论 CLD可以有效降低SCI术后CH的发生率,若联合HBO治疗效果更明显.Objective To discuss effects of early continuous lumbar drainage （CLD） combined with hyperbaric oxygen （HBO） on patients with postoperative chronic hydrocephalus （CH） of severe carniocerebral injury （SCI）.Methods Three hundred and ninety postoperative cases of SCI collected from our hospital were divided into 3 groups：group A,the early HBO combined with CLD group （130 cases）;group B,the CLD group （130 cases）;group C,the routine drug treatment group （130 cases）.Comparisons were made for the differences in rates of postoperative CH after SCI between groups within one year.Results Bates （or the number of cases） of CH occurred within one year for the 3 groups were as follows：group A 5.38%（7 Cases）,group B 12.31%（16 cases）,group C 21.54%（28 cases）.Differences in the rates for the 3 groups were compared by Chi-square test：the result of the comparison for group A and B was x2=3.864,P〈0.05,for group B and C was X2=3.939,P〈0.05,for group A and C was x2=14.560,P〈0.01.Conclusions CLD could effectively reduce rate of postoperative CH following SCI,with the effect being more obvious if it was combined with HBO.

关 键 词：重型颅脑损伤 慢性脑积水 腰池持续引流 高压氧 

分 类 号：R686[医药卫生—骨科学]