冠心病并发阻塞性睡眠呼吸暂停低通气综合征的相关因素  

Analysis of relative factors of coronary atherosclerotic heart disease and obstructive sleep apnea-hypopnea syndrome

作　　者：李虹[1] 张秀荣[1] 梁英[1] 杜以明[1] 徐冬梅[1] 

机构地区：[1]山东大学附属千佛山医院老年病科,山东济南250014

出　　处：《心脏杂志》2010年第4期576-578,583,共4页Chinese Heart Journal

摘　　要：目的:分析冠心病并发阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)的相关因素。方法:通过对冠心病患者进行睡眠呼吸监测,分为冠心病并发OSAHS患者90例(OSAHS组),冠心病不并发OSAHS患者30例(非OSAHS组)。对两组患者分别进行一般情况调查,身高、体质量指数(BMI)、颈围的测量,睡眠呼吸监测及肱-踝脉搏波传导速度(Ba-PWV)测定。结果:OSAHS组患者与非OSAHS组比较,BMI、颈围显著增加(P<0.01);有吸烟史和高血压病史的患者比例显著增加(P<0.05);BaPWV显著增快(P<0.01)。结论:肥胖、吸烟、高血压病及动脉粥样硬化均为冠心病并发OSAHS的相关因素。AIM： To analyze the relative factors of coronary atherosclerotic heart disease and obstructive sleep apnea-hypopnea syndrome （OSAHS） for early intervention and reduced incidence. METHODS： The experimental group consisted of 90 patients with coronary atherosclerotic heart disease who were diagnosed with OSAHS by polysomnography. Control group was comprised of 30 patients with coronary atherosclerotic heart disease but without OSAHS. Data such as general status, height, weight and neck circumference, parameters of polysomnography and Ba-PWV were collected from the two groups and compared. RESULTS： Compared with those parameters in the control group, neck circumference and body mass index （BMI） were higher in the experimental group （P〈0.01）, as well as the rate of patients with smoking habit or with hypertension （P〈0.05）. Ba-PWV in experimental group was also higher （P〈0.01）. CONCLUSION： Obesity, smoking, hypertension and atherosclerosis are the relative risk factors for coronary atherosclerotic heart disease and OSAHS.

关 键 词：冠状动脉疾病 阻塞性睡眠呼吸暂停低通气综合征 相关因素 肱-踝脉搏波传导速度 

分 类 号：R541.4[医药卫生—心血管疾病] R563.19[医药卫生—内科学]