应变及应变率成像评价尿毒症患者左、右心室心肌功能  

Strain and strain rate imaging in assessing myocardial function of left and right ventriculars in patients with uremia

作　　者：卢西梅[1,2] 高晓军[2] 贾莉[2] 宋喜焕[3] 卢茗[4] 

机构地区：[1]大连市儿童医院超声科,辽宁大连116012 [2]大连市友谊医院超声科,辽宁大连116001 [3]大连市友谊医院肾移植科,辽宁大连116001 [4]大连市友谊医院肾内科,辽宁大连116001

出　　处：《中国医学影像技术》2010年第6期1069-1072,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨应变及应变率成像评价尿毒症患者左、右心室心肌局部舒缩功能的价值。方法 34例尿毒症患者根据左心室肥厚与否分为左心室非肥厚组18例,左心室肥厚组16例。正常对照组为30名健康者。测量各组左、右心室壁基底段及中间段的最大应变(ε)、收缩期峰值应变率(SRs)、舒张早期应变率(SRe)和舒张晚期应变率(SRa)。结果左心室:各节段ε、SRs及SRe均为左心室非肥厚组和左心室肥厚组小于正常对照组,大部分节段左心室非肥厚组大于左心室肥厚组;SRa:左心室非肥厚组大于左心室肥厚组,左心室非肥厚组部分节段小于正常对照组,部分节段大于正常对照组,左心室肥厚组大部分节段小于正常对照组。右心室:各节段的ε、SRs及SRe均为左心室非肥厚组和左心室肥厚组小于正常对照组,SRa为正常对照组<左心室非肥厚组<左心室肥厚组。结论应变及应变率能敏感地定量评价尿毒症左、右心室心肌局部舒缩功能。Objective To investigate the value of strain and strain rate imaging in assessing contractile function and diastolic function of left ventricular and right ventricular in uremia patients.Methods Thirty-four patients with uremia were divided into 2 groups according to whether left ventricular was hypertrophic：18 patients in group of non-hypertrophic left ventricular and 16 patients in group of hypertrophic left ventricular.Thirty healthy adults were selected as control group.Strain（ε）,systolic peak strain rate（SRs）,early diastolic strain rate（SRe）and later diastolic strain rate（SRa）in the basal segments and middle segments of left and right ventriculars were measured.Results In left ventricular,ε,SRs and SRe of each segments in group of non-hypertrophic left ventricular and hypertrophic left ventricular were smaller than those in control group,and in subtotal segments they were higher in group of non-hypertrophic left ventricular than those in group of hypertrophic left ventricular.In group of non-hypertrophic left ventricular,SRa was higher than that in group of hypertrophic left ventricular.In partial segments,SRa was smaller in group of non-hypertrophic left ventricular than that in control group,and in partial segments was higher than that in control group.In subtotal segments,SRa was smaller in group of hypertrophic left ventricular than that in control group.In right ventricular,ε,SRs and SRe in group of non-hypertrophic left ventricular and hypertrophic left ventricular in each segment were smaller than those in control group,and SRa was the lowest in normal group and the highest in group of hypertrophic left ventricular.Conclusion Strain and strain rate imaging can assess contractile and diastolic functions of left and right ventriculars myocardium about uremia sensitively and quantitatively.

关 键 词：应变 应变率 尿毒症 心肌功能 

分 类 号：R540.45[医药卫生—心血管疾病] R541.1[医药卫生—内科学]