生化参数对老年急性冠脉综合征患者预后的影响  

Impact of biochemical parameters on the prognosis of elderly patients with acute coronary syndrome

作　　者：李敏[1] 徐冬梅[1] 

机构地区：[1]山东省千佛山医院,山东济南250014

出　　处：《齐鲁护理杂志》2010年第7期10-11,共2页Journal of Qilu Nursing

摘　　要：目的:探讨生化参数对经皮冠状动脉腔内血管介入术(PCI)治疗老年急性冠脉综合征(ACS)患者预后的影响。方法:对40例ACS患者在常规治疗的基础上行PCI,分别测定介入前、介入后12 h和介入后2周的生化项目,包括CK-MB、cTnI和hs-CRP,并观察症状体征和心电图的变化。结果:本组患者均CK-MB、cTnI符合ACS的动态变化,未发现术后再次升高的病例。PCI术后12 h血清hs-CRP水平较术前升高,有统计学意义(P<0.05),但2周后降至正常。结论:介入治疗可加剧冠脉局部炎症反应,使hs-CRP升高,随着血管开通以及他汀类药物的应用,炎症反应逐渐减轻。CK-MB、cTnI的介入前后变化在本组病例中符合ACS的一般规律。制订ACS介入治疗的临床护理指导原则是非常必要的。Objective： To study the impact of biochemical parameters on the prognosis of elderly patients with acute coronary syndrome（ACS） treated with percutaneous coronary Intervention（PCI）.Methods： 40 patients with ACS were treated with PCI based on routine treatment.The biochemical items including CK-MB,cTnI and hs-CRP were determined respectively before intervention,12 hours and 2 weeks after intervention,the signs and symptoms and ECG changes were observed.Results： CK-MB and cTnI accorded to the dynamic changes of ACS and no postoperative increase of CK-MB and cTnI was found again.The levels of serum hs-CRP increased in 12 hours after intervention compared with that before intervention（P 0.05）,but the levels decreased to normal after 2 weeks.Conclusion： Interventional therapy can exacerbate coronary local inflammatory reaction so that hs-CRP increased.The inflammatory response gradually reduced,with the blood vessel opened and Statins used.The changes of CK-MB and cTnI before and after intervention are in line with the general rules of ACS.It is necessary to develop guiding principles for clinical nursing care in the treatment of ACS with PCI.

关 键 词：急性冠状动脉综合征 经皮冠状动脉腔内血管介入术 生化参数 心脏标志物 

分 类 号：R473.5[医药卫生—护理学]