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作 者:李永生[1,2] 王定安[1,2] 李映芳 董宝财[1,2] 陶晶[1,2] 邹弘驹
机构地区:[1]云南省第一人民医院口腔颌面外科 [2]昆明医学院口腔系口腔病理教研室
出 处:《临床口腔医学杂志》1999年第1期23-24,共2页Journal of Clinical Stomatology
摘 要:目的探讨5%鱼肝油酸钠和平阳霉素对正常组织有无损害作用。方法:共4只微型猪,分别将5%鱼肝油酸钠注入每只猪的一侧上下唇组织中,平阳霉素注入另一侧上下唇,7天及14天后各处死两只动物,常规组织学处理标本,光镜观察。结果:5%鱼肝油酸钠组表现明显的肌纤维萎缩、消失,但无组织坏死;而平阳霉素组血管外组织无明显变化,仅见血管内、外壁增厚。结论:5%鱼肝油酸钠注入正常组织中会引起组织损害;平阳霉素对血管外正常组织无明显损伤。bjective To investigate the effect of 5% Sodium morrhuate and Pingyangmycin on normal tissue. Methods 4 Minipigs had been used in our study, 5% Sodium morrhuate was injected in pig's upper and lower lips of one side, and Pingyangmycin was injected in the other side. Every two animals were killed after 7 days and 14 days, and routinely historical observation had been made. Results The muscle fiber's wither and disappearance can be seen in all samples in the group of 5% Sodium morrhuate, no tissue necrosis was found; But in Pingyangmycin's group, only the wall of vascular became thickening and the tissues outside vascular are normal. Conclusion 5% Sodium morrhuate must be avoided injecting into normal tissue, it can cause normal tissue damaged; Pingyangmycin is safety to the tissues outside vascular.
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