高效薄层扫描法测定愈肝扶正胶囊中黄芪甲苷含量  

Quality control of Yugan Fuzheng capsule with HPTLCS

作　　者：王荣 赵兴红 胡晓丽 

机构地区：[1]兰州军区后勤部药物研究所 [2]兰州军区医学高等专科学校教务部

出　　处：《中国药学杂志》1999年第2期114-116,共3页Chinese Pharmaceutical Journal

摘　　要：目的：研究愈肝扶正胶囊质量控制方法。方法：运用高效薄层扫描法对该制剂中黄芪甲苷的含量进行测定。结果：薄层色谱斑点清晰，黄芪甲苷在２～１２μｇ范围内浓度与峰面积线性关系良好ｒ＝０９９９４，平均回收率为９８９％，ＲＳＤ为２００％。结论：建立的测定愈肝扶正胶囊中黄芪甲苷含量的方法简便、可靠，重现性好。OBJECTIVE:To provide a method of quality control for Yugan Fuzheng capsule (preparation of Chinese materia medica). METHOD:High performance thin layer chromatographic scanning (HPTLCS) was used for the determination of astragaloside Ⅳ in the preparation. RESULTS: The spots of astragaloside Ⅳ on the HPTLCS plate had a good linearity between its content and area within the range of 2～12μg( r=0 9994 ).The average recovery was 98.9%,and the RSD was 2.00%. CONCLUSION: This qualitative determination for astragaloside Ⅳ can be used as quality control because of its convenience,accuracy and good reproducibility.

关 键 词：愈肝扶正胶囊 高效薄层扫描法 黄芪甲苷 

分 类 号：R286.0[医药卫生—中药学]