卡泊芬净联合复方磺胺甲噁唑治疗艾滋病合并肺孢子菌肺炎  

Combined caspofungin and TMP-SMX treatment for PCP in AIDS patients

作　　者：江雪艳[1] 张仁芳[1] 郑毓芳[1] 刘莉[1] 沈银忠[1] 卢洪洲[1,2] 

机构地区：[1]上海市公共卫生临床中心感染一科,上海201508 [2]上海市华山医院传染科,上海200040

出　　处：《中国真菌学杂志》2010年第3期141-143,共3页Chinese Journal of Mycology

摘　　要：目的探讨卡泊芬净联合复方磺胺甲噁唑(TMP-SMX)治疗艾滋病合并肺孢子菌肺炎(PCP)的疗效。方法回顾性总结分析9例艾滋病合并肺孢子菌肺炎的临床资料,包括临床特点及诊疗经过。结果 9例患者临床诊断PCP成立,经卡泊芬净联合TMP-SMX抗PCP治疗后,除1例死亡(老年患者合并慢性支气管炎病史)外,其余8例均得到满意疗效。结论卡泊芬净联合TMP-SMX治疗艾滋病合并PCP,可达到良好的治疗效果。Objective To observe the efficacy of caspofungin combined with trimethoprim sulfamethoxazole （TMP-SMX） in the treatment of pneumocystis pneumonia （PCP） in AIDS patients. Methods Clinical feature,diagnosis and treatment procedure of nine PCP with AIDS patients were analyzed retrospectively. Results All of nine patients clinically diagnosed as PCP were administered with caspofungin and TMP-SMX. Eight patients acquired satisfied effects except one old with chronic obstructive pulmonary disease died. Conclusions Combined therapy of caspofungin and TMP-SMX has good efficacy for the treatment of PCP in AIDS patients.

关 键 词：卡泊芬净 复方磺胺甲噁唑 艾滋病 肺孢子菌肺炎 

分 类 号：R563.19[医药卫生—呼吸系统]