薄层扫描法测定复方“克清甲”软膏中苦参碱含量  

Determination on the Content of Matrine in Compound "Keqingjia" Cream by Single Wavelength Scanning Method

作　　者：李福杏[1] 雷春娟[2] 殷中琼[2] 魏琴[3] 吴长龙[2] 

机构地区：[1]成都农业科技职业学院,成都温江611130 [2]四川农业大学动物医学院,四川雅安625014 [3]宜宾学院发酵资源与应用四川省高校重点实验室,四川宜宾644003

出　　处：《安徽农业科学》2010年第16期8438-8439,共2页Journal of Anhui Agricultural Sciences

基　　金：教育部<长江学者和创新团队发展计划>创新团队项目(IR-TO848);宜宾市科学技术研究项目

摘　　要：[目的]测定复方＂克清甲＂软膏中苦参碱含量,建立其质量控制方法。[方法]采用单波长扫描法对制剂中的苦参碱含量进行检测。[结果]苦参碱含量在1-9μg时与吸收面积呈良好线性关系（R=0.995 2）;该品中苦参碱含量为0.02%。[结论]该测定方法专属性强、稳定性好、准确可靠,可作为复方＂克清甲＂软膏的质量控制方法。[Objective] The aim was to determine the content of matrine in compound ＂Keqingjia＂ cream and establish quality standard method.[Method] The content of matrine by single wavelength scanning method was determined.[Result] The study showed that the linear range of matrine was 1-9 μg（R=0.995 2）;The content of matrine in the cream was 0.02%.[Conclusion] The method of detection was accuracy,strong specificity and stability.It was suitable for the quality control of compound ＂Keqingjia＂ cream.

关 键 词：复方“克清甲”软膏 薄层扫描法 苦参碱 含量 

分 类 号：R927[医药卫生—药学]