超声造影观察射频治疗肝肿瘤疗效  

Evaluation of radiofrequency ablation therapy for hepatocellular carcinoma by contrast-enhanced ultrasonography

作　　者：黄声稀[1] 司芩[1] 钱晓莉[1] 吕校平[1] 仝威[1] 

机构地区：[1]解放军第八一医院特诊科,南京210002

出　　处：《医学研究生学报》2010年第6期631-633,共3页Journal of Medical Postgraduates

摘　　要：目的常规超声对肝肿瘤射频治疗后疗效评估较困难,探讨超声造影(contrast-enhanced ultrasonography,CEUS)在肝癌射频消融(radiofrequency ablation,RFA)治疗后肿瘤灭活诊断的临床应用价值。方法对病理确诊的43例肝癌患者69个病灶,RFA治疗前、后分别应用常规超声和CEUS对病灶大小、边界、内部回声、彩色多普勒血流信号、造影剂灌注情况进行对比分析。结果 CEUS对肿瘤灭活诊断的敏感性、特异性、准确性明显高于常规超声,分别为91.0%、94.4%、92.7%和47.8%、59.3%、53.6%。结论 CEUS能准确判断RFA对肿瘤消融的范围及程度,是一种判定射频治疗后疗效并能及时指导治疗的新方法。Objective The therapeutic effect of radiofrequency ablation（RFA） on hepatocellular carcinoma is difficult to be evaluated by conventional ultrasound.This study aimed to explore the clinical application value of contrast-enhanced ultrasonography（CEUS） in detecting hepatocellular carcinoma deactivation after RFA treatment.Methods We examined 69 lesions of pathologically confirmed hepatocellular carcinoma in 43 patients by conventional ultrasound and CEUS,and comparatively analyzed their sizes,borders,inner echoes,color Doppler blood flow signals and contrast agent perfusion characteristics before and after RFA treatment.Results CEUS showed significantly higher sensitivity,specificity and accuracy（91%,94.4% and 92.7%） than conventional ultrasound（47.8%,59.3% and 53.6%） in detecting deactivation and residues of the tumor after RFA therapy.Conclusion CEUS,as a new means of evaluating the efficacy of RFA and providing timely guidance to treatment,can accurately detect the range and degree of hepatocellular tumor ablation after RFA therapy.

关 键 词：肝癌 射频消融 超声造影 常规超声 

分 类 号：R445.1[医药卫生—影像医学与核医学]