心脏大血管的衰老及相关因素分析  

The Aging of the Large Arteries of the Heart and its Affective Factors

作　　者：王佩显[1] 周文[1] 郭倩玉[1] 李晓春[1] 黄灿亮[1] 孙琪[1] 赵向东[1] 

机构地区：[1]天津医科大学总医院心内科,300052

出　　处：《医学理论与实践》1999年第3期130-133,共4页The Journal of Medical Theory and Practice

摘　　要：为观测心脏大血管的增龄性改变,分析其相关因素。随机选取天津市高校健康教师316名,分成五个年龄组,行超声心动图检查。结果:(1)主动脉径从50岁起开始增宽,增宽部位在窦管连接处及其以远的升主动脉(D_AAo)。主动脉径与年龄相关(r=0.443,P<0.001),回归方程为:Y=24.55±0.085×Age(岁);(2)主动脉壁的运动幅度(A_Ao)随增龄而下降(r=0.379,P<0.001),回归方程为:Y=9.058—0.036×Aee(years);(3)肺动脉随增龄有增宽趋势,但无统计学意义。相关因素分析:A_Ao吸烟组低于非吸烟组(P<0.01);A型性格组(0.90±0.16cm)低于B型组(1.01±0.18),P<0.05。内向型性格组与外向组比较,A_Ao趋向降低(O.79±0.17vs 1.03±0.19),D_AAo趋向增宽(3.29±0.36vs3.16±0.39),但均无统计学意义。本文提示出大血管衰老的一般规律,即随增龄D_AAo增宽及A_Ao下降;促衰老的相关因素有:吸烟、A型性格和内向型性格;推论大血管管径及管壁僵度的变化对心血管系统的功能会产生一定的影响。To reveal the changes in aorta and pulmonary artery with aging,and find its relative factors. Three hundred and sixteen normal healthy intllectuals from four Tianjin universities were selected randomly and divided into five age groups. Echocardiograhic examination was perfomed in all of them, and obtained data was analysed statistically. The dimesion of aortic root has a possitive correlation with age,the regression formula as: Y = 24. 55±0. 085×age (years). The aortic root dilation begins at the age of 50 years,and localized to the sinus-tubular junction and proximal ascending aorta. The ampitude of aortic wall movement (AAo)negatively correlated with age (r= -0. 379, P < 0. 001) the regression formula as:Y = 0. 058-0. 036×age (years). The pulmonary artery appears to have a tendency to dilation,but no significant changes with aging,the AAoin smoking group (0. 89- 25cm) is lower than nonsmoking one (1. 12 + 0. 24cm), P < 0. 01; AAoin type A personality group(0. 90-16) is lower then type B one (1. 01-18), P < 0. 05. With aging,the dimension of aortic root is getting wider and wider,which begins at age of 50 years,and localized to the sinus-ubular juntion and especially to ascending aorta;the amplitude of aortic wall is getting lower and lower. In contrast,the pulmonary artery no significant changes with age. There are some risk factors which may promote and worsen the aortic changes mentioned above,including smoking,A thpe personality and etc.

关 键 词：主动脉 肺动脉 超声心动图 衰老 

分 类 号：R339.38[医药卫生—人体生理学]