针刺足三里的脊髓背根神经电信号非线性特征提取  

Nonlinear characteristics extraction from electrical signals of dorsal spinal nerve root evoked by acupuncture at Zusanli point

作　　者：韩春晓[1] 王江[1] 车艳秋[1] 邓斌[1] 郭义[2] 郭永明[2] 刘阳阳[2] 

机构地区：[1]天津大学电气与自动化工程学院,天津300072 [2]天津中医药大学针灸学院,天津300193

出　　处：《物理学报》2010年第8期5880-5887,共8页Acta Physica Sinica

基　　金：国家自然科学基金重点项目(批准号:50537030);国家自然科学基金(批准号:30672716);国家自然科学基金青年科学基金(批准号:50707020;50907044;60901035);中国博士后科学基金(批准号:20070410756;200801212;20080430731;20080430090;200902275)资助的课题~~

摘　　要：神经系统在外部刺激下会呈现出丰富的放电模式,针刺作为对穴位的机械作用可以等效为对神经系统的一种外部刺激,在针刺刺激下神经系统会产生不规则的电信号.由于神经系统是高度复杂的非线性动力学系统,神经电信号具有很强的非线性,所以本文设计了提插补法、提插泻法、捻转补法、捻转泻法等四种针刺手法的动物实验,获取针刺大鼠足三里穴位的脊髓背根神经束动作电位序列.采用峰峰间期的思想,应用非线性时间序列的方法分析此动作电位序列,通过计算Lyapunov指数、关联维数以及Lempel-Ziv复杂度等参数,提取神经电信号的非线性特征,得到不同针刺手法的神经电信息的编码;并证明了针刺作用下脊髓背根的神经电信号具有明显的混沌特性.Neural system generates various kinds of fire patterns when stimulated by external or internal inputs. Acupuncture,as a mechanical action,is equivalent to an external stimulus to the neural system. When stimulated by the acupuncture,the neural system can evoke irregular electrical signals. Neural system is a complex nonlinear dynamic system that possesses strong nonlinear characteristic,so it is necessary to introduce the nonlinear time series analysis method to study the neural electrical signal. In this paper,an experiment is designed in which acupuncture is made at Zusanli with four different acupuncture manipulations to obtain action potentials on dorsal spinal nerve root. The concept of the interspike interval （ISI） is used for the study of the acupuncture electrical signals. Several nonlinear characteristic parameters are extracted, such as the Lyapunov exponent,correlation dimension and Lempel-Ziv complexity,and the neural coding of the electrical signal evoked by different acupuncture manipulations is obtained. It is also shown that under the effect of the acupuncture, the electrical signals of dorsal spinal nerve root based on acupuncture at Zusanli point has distinguished chaotic features.

关 键 词：针刺 神经电信号 非线性分析 混沌 

分 类 号：R245[医药卫生—针灸推拿学]