β-丁香烯含量测定的药典方法研究  

Study on pharmacopoeia method for determination of β-caryophyllene

作　　者：鲁辉[1] 顾炳仁 缪刚[2] 许奇[2] 杨世林[1] 谢洪平[1] 

机构地区：[1]苏州大学药学院,苏州215123 [2]苏州市药品检验所,苏州215002

出　　处：《药物分析杂志》2010年第7期1177-1181,共5页Chinese Journal of Pharmaceutical Analysis

基　　金：国家药典委员会2010版药典修订项目(No:TS-38)

摘　　要：目的:建立药用牡荆油中β-丁香烯含量测定的药典方法。方法:采用气相色谱建立含量测定方法,对不同来源牡荆油进行测定,并进行方法学和普适性研究。结果:建立了牡荆油中β-丁香烯GC含量测定的药典方法,获得了不同来源牡荆油中β-丁香烯的含量分布范围。结论:方法准确度高、分析时间短、重现性及耐用性好,具有广泛的适用性,可以作为药典中牡荆油的含量测定方法。Objective：To establish the pharmacopoeia method for determination of β-caryophyllene in medicinal Oleum Viticis Negundo.Methods：Established the gas chromatography method and used it to determine β-caryophyllene in the Oleum Viticis Negundo with the different sources,and then studied the methodology and universality of the method.Results：Have established the pharmacopoeia method for determination of β-caryophyllene and obtained the content range of β-caryophyllene in medicinal Oleum Viticis Negundo.Conclusion：The method is of good accuracy,reproducibility and ruggedness.The analytic time is short and the adaptivity is wide.It can be used as pharmacopoeia method for determination of β-caryophyllene in medicinal Oleum Viticis Negundo.

关 键 词：β-丁香烯 牡荆油 中国药典 气相色谱 

分 类 号：R917[医药卫生—药物分析学]