纯化布氏菌素与旧菌素对布氏菌活菌苗免疫人群的皮试动态分析  

KINETIC ANALYSIS OF SKIN TESTS FOR PURIFIED BRUCELLIN AND OLD BRUCELLIN IN PERSONS VACCINATED WITH ATTENUANT BRUCELLA LIVE VACCINE

作　　者：李恪梅[1] 刘志臣 赵恒云 苏城[1] 黄建[1] 

机构地区：[1]中国药品生物制品检定所 [2]辽宁省西丰县地方病防治所 [3]辽宁省卫生防疫站

出　　处：《中国地方病防治》1999年第1期6-8,共3页Chinese Journal of Control of Endemic Diseases

摘　　要：用纯化布氏菌素和旧菌素对布氏活菌苗免疫人群按同体双臂法测定免疫后1、3、6、9、12月5个不同时间的动态阳性率及反应强度比较。结果表明免疫后3个月为阳转高峰,6个月开始下降,12个月为0。两种菌素阳转率基本一致(P>0.05)无显著性差异,总符合率为84.0％,但纯化菌素反应强度明显小于旧菌素。Comper with positive rate and reaction intensity of skin tests with purified brucellin(P. B.) and old brucellin (O.B.) on both arms vaccinated persons with attenuant brucella live vaccine after 1,3, 6, 9 and 12 months were reported in this paper. The result showed that the peak of positive rate was in third month, and began to decrease in sixth month, and disappear after 12 months. No significant statistical difference was discovered between P.B. and O.B. ( P >0.05). Total coincident rate is 84.0% , reaction intensity of P.B. is less than reaction intensity of O.B. .

关 键 词：布氏菌素 免疫人群 阳性率 动态分析 

分 类 号：R392－33[医药卫生—免疫学] R516.7[医药卫生—基础医学]