大叶石头花中的黄酮碳苷(英文)  

C-Glycosylflavonoids from the Aerial Part of Gypsophila pacifica

作　　者：聂韡[1] 罗建光[1] 孔令义[1] 

机构地区：[1]中国药科大学天然药物化学教研室,南京210009

出　　处：《中国天然药物》2010年第4期250-252,共3页

基　　金：supported by the National Natural Science Foundation of China for Outstanding Young Scientists (No. 30525032)~~

摘　　要：目的：研究大叶石头花地上部分的黄酮碳苷成分。方法：用70%乙醇回流提取,氯仿和正丁醇依次萃取,采用硅胶、SephadexLH-20、ODS柱色谱等方法分离纯化,根据理化性质和光谱数据鉴定化合物的结构。结果：从大叶石头花地上部分分离得到6个黄酮碳苷：皂草黄素（isovitexin,1）,芒果素（mangiferin,2）,异荭草素（isoorientin,3）,2＇＇-O-鼠李糖基-7-甲氧基异荭草素（4）,2＇＇-O-鼠李糖基皂草黄素（5）,2＇＇-O-鼠李糖基异荭草素（6）。结论：化合物1~6首次从该属中分离得到。AIM：To study the C-glycosylflavonoids from the aerial parts of Gypsophila pacifica Kom.METHODS：The C-glycosylflavonoids were isolated by various column chromatographic methods and their structures were identified by spectral data together with physicochemical analysis.RESULTS：Six known compounds were isolated and identified as isovitexin（1）,mangiferin（2）,isoorientin（3）,2＇＇-O-rhamnopyransoyl-7-methoxylisoorientin（4）,2＇＇-O-rhamnopyransoyl-isovitexin（5）,and 2＇＇-O-rhamnopyransoyl-isoorientin（6）.CONCLUSION：The six compounds were isolated from the genus Gypsophila for the first time.

关 键 词：大叶石头花 石竹科 黄酮碳苷 

分 类 号：R284.1[医药卫生—中药学]