油桐根的化学成分(英文)  

Chemical Constituents from the Roots of Vernicia fordii

作　　者：谢郁峰[1] 陶正明[2] 王红兵[3] 秦国伟[3] 

机构地区：[1]广东药学院,广州510006 [2]浙江省亚热带作物研究所,温州325005 [3]中国科学院上海药物研究所,上海201203

出　　处：《中国天然药物》2010年第4期264-266,共3页

基　　金：supported by Young Research Grant from Chinese Academy of Sciences (No. SIMM0709QN-05)~~

摘　　要：目的:对大戟科植物油桐(Vernicia fordii(Hemsl.)Airy Shaw)根的化学成分进行研究。方法:运用多种层析方法进行分离纯化,通过波谱解析进行结构鉴定。结果:从油桐根的乙醇提取物中分离并鉴定出6种成分,它们是12-O-palmityl-13-O-acetyl-16-hydroxyphorbal(1),aleuritin(2),(-)syringaresinol(3),daucosterol(4),4-hydroxy-3,5-dimethoxybenzolicacid(5)和acetylaleuritolic acid(6).其中1和2首次从根中分得,并补充了一些NMR研究。结论:化合物3-6为本植物中首次报道,6是齐墩果烷型三萜,结构中具有△14,15,在天然界较少见。AIM：To study the chemical constituents of the roots of Vernicia fordii（Hemsl.） Airy Shaw（Euphorbiaceae）.METHODS：Compounds were isolated by repeatedly column chromatography over silica gel and Sephadex LH-20.Their structures were identified by spectral analysis and comparison with the literature.RESULTS：Six compounds were isolated and identified as 12-O-palmityl-13-O-acetyl-16-hydroxyphorbal（1）,aleuritin（2）,（-） syringaresinol（3）,daucosterol（4）,4-hydroxy-3,5-dimethoxybenzolic acid（5） and acetyl aleuritolic acid（6）.CONCLUSION：Compounds 3-6 were reported from the plant for the first time.

关 键 词：油桐根 化学成分 二萜 

分 类 号：R284.1[医药卫生—中药学]