海洋微生物次生代谢产物的结构特征和生物活性的研究进展  

Research Progress on Bioactive Metabolites from Marine Microorganism and Their Structures

作　　者：王幸[1] 吴文惠[1] 陈志华[1] 张洁[1] 包斌[1] 

机构地区：[1]上海海洋大学食品学院,上海201306

出　　处：《中国天然药物》2010年第4期309-320,共12页

基　　金：上海市自然科学基金项目和重点学科建设项目(No.10ZR1413800;J50704)~~

摘　　要：本文归纳了21世纪以来海洋微生物产生的次生代谢产物的结构类型及其抗菌、抗肿瘤、抗心脑血管疾病、抗炎症和酶抑制等生物活性,并展望了今后海洋微生物和海洋天然产物的发展方向。Base on the literature of marine natural products published from 2000 to 2009,the metabolites isolated from marine microorganisms and their bioactivities,such as antibacterial,antitumor,anti-cardiovascular,anti-inflammatory and enzyme inhibitory activities,are summarized in this paper.And a perspective in regard to the future development of the marine natural products is also made by the author.

关 键 词：海洋微生物 次生代谢产物 生物活性 

分 类 号：R931.77[医药卫生—生药学]