缺氧缺血性脑病脑水肿量化诊断方法探讨  

Quantitative diagnosis of hypoxic ischemic encephlopathy

作　　者：管婉华[1] 陈欣林[1] 周晓珊[1] 李宁[1] 

机构地区：[1]湖北省妇幼保健院

出　　处：《河南医科大学学报》1999年第1期83-85,共3页Journal of Henan Medical University

摘　　要：目的：为了探讨缺氧缺血性脑病（ＨＩＥ）量化诊断方法。方法：对正常新生儿３５例，ＨＩＥ１５例，使用Ａｃｕｓｏｎ１２８×Ｐ／１０电脑声像仪，Ｖ７１４扇扩探头及Ｌ７高频线阵探头，经耳郭上方双侧颞侧，直接检测蛛网膜与脑沟及蛛网膜与脑回的间隙，并同时测双侧大脑皮层血流，于日龄１、３、５ｄ连续检测。结果：正常新生儿蛛网膜下腔间隙显示清晰，结构稳定，蛛网膜与脑沟之间的间隙为１９３～２．３３ｍｍ，与脑回之间的间隙１４４～１６４ｍｍ，而１５例ＨＩＥ患儿大脑皮层沟、回结构显示不清，沟、回起伏结构消失，蛛网膜下腔间隙显示不清。动态观察随患儿病情逐渐好转，蛛网膜与脑沟之间的间隙由０７６ｍｍ增至１９１ｍｍ，与脑回之间的间隙由００６ｍｍ增至０２９ｍｍ。结论：测量蛛网膜下腔间隙，方法简便、无创、数据可靠，可作为ＨＩＥ脑水肿量化诊断指标。Aim:To study quantitative diagnosis of hypoxic ischemic encephlopathy(HIE). Methods:The depths of the subarachnoid and the bloodstream of each side of cerebral cotex in 35 normal infants and 15 HIE at the ages of 1,3 and 5 days were examined by ultrasonography. Results: In normal infants, the subarachnoid spaces were showed clearly, the structure was stable, the space between the arachhoid and the sulcus was 1.93～2 33 mm, and the space between the arachnoid and the gyrus was 1.44～1.64 mm. The wave structures of the sulcus and gyrus of 15 HIE infants were not clear. With HIE infant's recovering,the spaces between the arachnoid and the sulcus, and the gyrus extended to 1.91 mm and 0.29 mm, respectively. Conclusion:The method measuring the arachnoid is easy and reliable.It can be used as the index of the quantitative diagonosis when the brain edema is diagnosed.

关 键 词：彩色多普勒 缺氧缺血性脑病 脑水肿 诊断 

分 类 号：R722.120.6[医药卫生—儿科] R742.704[医药卫生—临床医学]