包皮中人乳头瘤病毒感染的临床意义  

The significance for treatment of human papillomavirus infection in foreskin

作　　者：马胜利[1] 胡礼泉[1] 郑新民[1] 鲁德银[2] 

机构地区：[1]湖北医科大学附属第二医院泌尿外科,武汉430071 [2]湖北医科大学病毒研究所

出　　处：《临床泌尿外科杂志》1999年第3期116-118,共3页Journal of Clinical Urology

摘　　要：目的:探讨包皮中人乳头瘤病毒感染的临床意义。方法:采用PCR-DNA扩增的方法检测了48例包皮环切标本中HPV-6、11、16、18及33型的DNA保守片段。结果:48例中,20例阳性,阳性率为41.7%;其中不同年龄段、有无包皮垢及有无感染史组间HPV阳性率均无显著性差异。结论:对需行包皮环切的男孩,应尽早施行包皮环切术。只有尽早消灭致癌因素,才有可能对阴茎癌起到预防作用。Purpose:To ascertain the significance for treatment of Human Papillomavirus (HPV) infection in foreskin.Methods:We used a polymerase chain reaction (PCR) based assay to test 48 specimens of circumcision for the presence of HPV type6,11,16,18,and 33 DNA.Results:The positive rate of HPV DNA was 41.7 %(20/48) and there were no significant difference on HPV infection in different groups of age,smegma and history of balanoposthitis.Conclusions:Boys should perform circumcision as early as possible.

关 键 词：包皮环切术 HPV 包茎 聚合酶链反应 

分 类 号：R697.12[医药卫生—泌尿科学] R373.9[医药卫生—外科学]