哮喘控制测试与最大呼气峰流速相关性的探讨  

Investigation on the correlation of asthma control test and peak expiratory flow rate

作　　者：高忻[1] 荣光生 盛俐[1] 姚君[1] 童艳[1] 

机构地区：[1]合肥市第三人民医院儿科,安徽合肥230022 [2]合肥市第三人民医院呼吸科,安徽合肥230022

出　　处：《皖南医学院学报》2010年第4期268-270,共3页Journal of Wannan Medical College

基　　金：合肥市重点科研基金项目(2007-1008)

摘　　要：目的:观察在儿童哮喘缓解期阶梯治疗中,哮喘控制测试(asthma control test,ACT)与最大呼气峰流速(PEF)作用的相关性。方法:选择我院儿科哮喘门诊就诊的58例哮喘患儿,吸入糖皮质激素(inhaled corticosterids,ICS)进行缓解期的阶梯治疗。要求患儿家庭每日早、晚监测PEF,并以图表形式记录。每月哮喘门诊复诊一次,了解PEF值、PEF占个人预计值的百分比(PEFpred%),PEFpred%≥个人预计值80%为哮喘控制,<个人预计个值80%为哮喘未控制,同时进行ACT问卷,计算得分,<20分为哮喘未控制;20～25分为哮喘控制。结果:ACT评分<20分组与ACT评分20～25分组PEFpred%比较,差异有统计学意义(P<0.01)。PEFpred%<个人预计值80%组与PEFpred%≥个人预计值80%组ACT评分比较,差异有统计学意义(P<0.01)。ACT评分与PEFpred%具有线性相关关系,P<0.001。结论:ATC评分与患儿的PEF具有良好的相关性,对于不能监测PEF的婴幼儿哮喘可以用ACT评分作为评估哮喘控制的指标,指导阶梯治疗。Objective：To observe the correlation significance of stepped therapy in remission of asthma in children by asthma control test（ACT） and peak expiratory flow （PEF）.Methods：We selected 58 out-patient children with asthma in our hospital and carried out the stepped therapy in remission with inhaled corticosteroids（ICS）,and the parents of the patients were asked to monitor PEF daily in the morning and evening by filling the chart. The patients were supposed to have an outpatient visit once a month for calculating PEF value and percentage of the predicted value in PEF of each individual（PEFpred%）. The asthma was thought to be under control by value of PEFpred%≥80%,whereas,PEFpred% 80% was failure. Also,ACT questionnaire was conducted for the scores,and the scores20 on the list indicated failure of control,while those of 20～25 were thought to be well controlled. Results：Comparison of PEF pred% between ACT score 20 and the one 20~25 suggested statistical difference（P0.01）. By ACT scores,PEFpred%80% were also different from PEFpred%≥80% （P0.01）. ACT scores were linearly correlated with PEFpred%. Conclusion：The results of ACT scores and PEFpred% in children with asthma may present with good correlation. In some young asthmatic children incapable of being monitored PEF,ACT scores can be valuable marker in rating the management of asthma and as directions to stepped care.

关 键 词：儿童哮喘 阶梯治疗 哮喘控制测试 最大呼气峰流速 吸入糖皮质激素 

分 类 号：R725.6[医药卫生—儿科]