稳心颗粒对扩张型心肌病患者窦性心率震荡的影响研究  

TheInfluence of Buchangwenxin Granule on Heart Rate Turbulence in Patients with Dilated Cardiomyopathy

作　　者：余华[1] 许向东[1] 叶兴文[1] 付娟[1] 袁媛[1] 

机构地区：[1]江西九江学院附属医院心血管内科,332000

出　　处：《实用心脑肺血管病杂志》2010年第7期863-864,共2页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的探讨稳心颗粒对扩张型心肌病(DCM)患者窦性心率震荡(HRT)的影响。方法入选扩张型心肌病患者42例作为心肌病组,选择本院体检中年龄、性别相匹配的健康人50名作为正常组,比较两组研究对象的震荡起始(TO)及震荡斜率(TS)值有无统计学差异。将心肌病组随机分为对照组及稳心颗粒组,4周后两组病人再行24h动态心电图记录,取得TO及TS值,再进行统计学比较和分析。结果心肌病组TO与TS均明显异常,与正常组比较有显著性差异(P<0.05),稳心颗粒组与对照组比较TO负值明显增高,TS明显增大(P<0.05)。结论扩张型心肌病患者的HRT较正常人群减弱或消失,稳心颗粒可使异常的HRT有所恢复,减少室性心律失常和心脏性猝死的发生。Objective To explore the therapeutic efficacy of Buchangwenxin Granule on HeartRate Turbulence in dilated cardiomyopathy.Methods 42 patients with dilated cardiomyopathy were chosen as the dilated cardiomyopathy（DCM） group,and 50 healthy people whose sex and age matching with the DCM group as the normal group to see if there are statistical difference between TO and TS of the two groups.Then the patients of the DCM group were divided at random into the control group and the group treated with Buchangwenxin.4 weeks later,the patiens of the two groups were monitored with 24 dynamic electrocardiogram and the results were recorded.At last the values of TO and TS were taken for statistical comparison and analysis.Results Both TO and TS of the DCM group Markedly abnormal Compared with the normal group（P0.05）.The negtive value of TO of the group treated with Buchangwenxin Granule increased significantly and TS rose obviously Compared with the control group（P0.05）.Conclusion Compared with normal population,HRT in patients with dilated cardiomyopathy significantly abnormal and Buchangwenxin Granule can somewhat restore abnormal HRT,reducing ventricular arrhythmia and sudden cardiac death from occurring.

关 键 词：稳心颗粒 扩张型心肌病 窦性心率震荡 

分 类 号：R541[医药卫生—心血管疾病]