硝酸铈对大白鼠体内乙酰胆碱酯酶活性的影响  

Effect of Ce(NO 3) 3 on Acetycholinesterase Activity

作　　者：田峻[1,2] 苏应娟[1,2] 龚孟濂[1,2] 雷衡毅[1,2] 杨燕生[1,2] 

机构地区：[1]中山大学化学与化工学院 [2]中山大学生命科学学院

出　　处：《中山大学学报（自然科学版）》1999年第2期121-123,共3页Acta Scientiarum Naturalium Universitatis Sunyatseni

基　　金：国家自然科学基金;广东省自然科学基金

摘　　要：ＳＤ成年大鼠一次性腹腔注射１５０ｍｇ／ｋｇ的硝酸铈，分别于３，６，１２，２４，４８ｈ后处死，测定其脑、肌肉组织的乙酰胆碱酯酶的活性．结果表明：脑、肌肉受硝酸铈影响有相似的规律．在注射初期，酶活性显著降低，经过一段时间后，又逐渐恢复．The effect of Ce(NO 3) 3 on AchE activity in rats was investigated The rats were treated with intraperitoneal injection of a single dose of 150 mg/kg Ce(NO 3) 3 and killed 3,6,12,24 or 48 hours later after the injection The AchE activity of brain and musle was measured with spectrophotometry The results show that the AchE activity of brain was affected by Ce(NO 3) 3 similar to that of musle At the beginning,the AchE activity fell down notably,and then it recovered to normal

关 键 词：硝酸铈 乙酰胆碱酯酶 活性 稀土离子 水解酶 

分 类 号：Q556.9[生物学—生物化学] R965.2[医药卫生—药理学]